(2-(((tert-Butoxycarbonyl)amino)methyl)phenyl)boronic acid

Base Information

Chemical Name:(2-(((tert-Butoxycarbonyl)amino)methyl)phenyl)boronic acid
CAS No.:433969-27-8
Molecular Formula:C12H18 B N O4
Molecular Weight:251.09
Hs Code.:2918990090
DSSTox Substance ID:DTXSID80448143
Wikidata:Q82267098
Mol file:433969-27-8.mol

Synonyms:433969-27-8;(2-(((tert-Butoxycarbonyl)amino)methyl)phenyl)boronic acid;2-[(Boc-amino)methyl]phenylboronic Acid;2-BOC-AMINOMETHYL-PHENYLBORONIC ACID;[2-[[(2-methylpropan-2-yl)oxycarbonylamino]methyl]phenyl]boronic Acid;2-((tert-butoxycarbonylamino)methyl)phenylboronic acid;2-(TERT-BUTOXYCARBONYL)BENZYLAMINEBORONIC ACID;MFCD05663974;[2-({[(tert-butoxy)carbonyl]amino}methyl)phenyl]boronic acid;2-[(Boc-amino)methyl]phenylboronicAcid;(2-{[(tert-Butoxycarbonyl)amino]methyl}phenyl)boronic acid;SCHEMBL3490988;DTXSID80448143;NVCGSIBAXVRMLU-UHFFFAOYSA-N;AKOS015991297;AB22095;BS-2068;SY017591;CS-0119962;EN300-4346621;A872703;2-(tert-butoxycarbonylaminomethyl)phenylboronic acid;2-(tert-butoxycarbonylaminomethyl)-phenylboronic acid

Suppliers and Price of (2-(((tert-Butoxycarbonyl)amino)methyl)phenyl)boronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
2-Boc-Aminomethyl-phenylboronic acid
50mg
$ 413.00

Sigma-Aldrich
2-(tert-Butoxycarbonylaminomethyl)phenylboronic acid pinacol ester Aldrich
1g
$ 615.00

Matrix Scientific
2-(tert-Butoxycarbonyl)benzylamineboronic acid
1g
$ 978.00

Matrix Scientific
2-(tert-Butoxycarbonyl)benzylamineboronic acid
500mg
$ 775.00

J&W Pharmlab
2-Boc-aminomethyl-phenylboronicacid 97%
25g
$ 2320.00

J&W Pharmlab
2-Boc-aminomethyl-phenylboronicacid 97%
1g
$ 170.00

J&W Pharmlab
2-Boc-aminomethyl-phenylboronicacid 97%
5g
$ 580.00

Crysdot
(2-(((tert-Butoxycarbonyl)amino)methyl)phenyl)boronicacid 95+%
5g
$ 744.00

Biosynth Carbosynth
2-Boc-Aminomethyl-phenylboronic acid
1 g
$ 1018.40

Biosynth Carbosynth
2-Boc-Aminomethyl-phenylboronic acid
250 mg
$ 230.00

Total 23 raw suppliers

Chemical Property of (2-(((tert-Butoxycarbonyl)amino)methyl)phenyl)boronic acid

Chemical Property:

Melting Point:190-192 °C
PKA:8.53±0.53(Predicted)
PSA：78.79000
Density:1.15±0.1 g/cm3(Predicted)
LogP:0.78200
Storage Temp.:2-8°C
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:251.1328882
Heavy Atom Count:18
Complexity:278

Purity/Quality:

97% ^*data from raw suppliers

2-Boc-Aminomethyl-phenylboronic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:B(C1=CC=CC=C1CNC(=O)OC(C)(C)C)(O)O

Technology Process of (2-(((tert-Butoxycarbonyl)amino)methyl)phenyl)boronic acid

There total 6 articles about (2-(((tert-Butoxycarbonyl)amino)methyl)phenyl)boronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 162356-90-3
N-(tert-butoxycarbonyl)-2-bromobenzylamine

: 433969-27-8
2-((tert-butoxycarbonylamino)methyl)phenylboronic acid

Guidance literature:: Multistep reaction.;
DOI:10.1021/jm0210461

Reference yield: 98.0%

: 5419-55-6
Triisopropyl borate

: 162356-90-3
N-(tert-butoxycarbonyl)-2-bromobenzylamine

: 433969-27-8
2-((tert-butoxycarbonylamino)methyl)phenylboronic acid

Guidance literature:: N-(tert-butoxycarbonyl)-2-bromobenzylamine; With methyllithium; In tetrahydrofuran; diethyl ether; at -78 ℃; for 1h; Inert atmosphere;

With tert.-butyl lithium; In tetrahydrofuran; diethyl ether; hexane; at -78 ℃; for 1h; Inert atmosphere;

Triisopropyl borate; Further stages;
DOI:10.1111/bph.12409