Technology Process of C18H17ClO8
There total 5 articles about C18H17ClO8 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
copper(I) oxide; sulfuric acid; hypophosphorous acid; sodium nitrite;
In
methanol; water;
at 0 - 20 ℃;
DOI:10.1021/ol400549q
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: aluminum (III) chloride / dichloromethane / 1 h / 20 °C
2.1: potassium carbonate / acetone / 0.5 h / 0 - 20 °C
3.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h / 0 °C
3.2: 0 - 20 °C
4.1: palladium 10% on activated carbon; hydrogen / ethyl acetate / 0.5 h / 760.05 Torr
5.1: hypophosphorous acid; sulfuric acid; copper(I) oxide; sodium nitrite / methanol; water / 0 - 20 °C
With
copper(I) oxide; aluminum (III) chloride; sulfuric acid; palladium 10% on activated carbon; hydrogen; hypophosphorous acid; sodium hydride; potassium carbonate; sodium nitrite;
In
methanol; dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide; acetone;
DOI:10.1021/ol400549q
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h / 0 °C
1.2: 0 - 20 °C
2.1: palladium 10% on activated carbon; hydrogen / ethyl acetate / 0.5 h / 760.05 Torr
3.1: hypophosphorous acid; sulfuric acid; copper(I) oxide; sodium nitrite / methanol; water / 0 - 20 °C
With
copper(I) oxide; sulfuric acid; palladium 10% on activated carbon; hydrogen; hypophosphorous acid; sodium hydride; sodium nitrite;
In
methanol; water; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1021/ol400549q
