Technology Process of C46H70N4O11
There total 9 articles about C46H70N4O11 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(2-octyloxy-5-undec-10-enoylaminobenzoylamino)acetic acid;
With
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine;
In
dichloromethane;
at 20 ℃;
for 0.5h;
Inert atmosphere;
C18H28N2O7;
In
dichloromethane;
at 20 ℃;
for 48h;
Inert atmosphere;
DOI:10.1021/ol201282d
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: water; potassium hydroxide / methanol / 7 h / 60 °C
2.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 0.5 h / 20 °C
3.1: triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere
4.1: 25% Pd/C; hydrogen / dichloromethane / 24 h
5.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / dichloromethane / 0.5 h / 20 °C / Inert atmosphere
5.2: 48 h / 20 °C / Inert atmosphere
With
oxalyl dichloride; 25% Pd/C; water; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; N,N-dimethyl-formamide; potassium hydroxide;
In
methanol; dichloromethane;
DOI:10.1021/ol201282d
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere
2.1: 25% Pd/C; hydrogen / dichloromethane / 24 h
3.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / dichloromethane / 0.5 h / 20 °C / Inert atmosphere
3.2: 48 h / 20 °C / Inert atmosphere
With
25% Pd/C; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine;
In
dichloromethane;
DOI:10.1021/ol201282d
