({2'-[(4-{(tert-butoxycarbonyl)[2-(2-pyridinyl)ethyl]amino}anilino)carbonyl]-1,1'-biphenyl-4-yl}oxy)acetic acid

Base Information

• Chemical Name: ({2'-[(4-{(tert-butoxycarbonyl)[2-(2-pyridinyl)ethyl]amino}anilino)carbonyl]-1,1'-biphenyl-4-yl}oxy)acetic acid
• CAS No.: 408366-80-3
• Molecular Formula: C₃₃H₃₃N₃O₆
• Molecular Weight: 567.642

Synonyms:({2'-[(4-{(tert-butoxycarbonyl)[2-(2-pyridinyl)ethyl]amino}anilino)carbonyl]-1,1'-biphenyl-4-yl}oxy)acetic acid

Chemical Property of ({2'-[(4-{(tert-butoxycarbonyl)[2-(2-pyridinyl)ethyl]amino}anilino)carbonyl]-1,1'-biphenyl-4-yl}oxy)acetic acid

Chemical Property:

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Technology Process of ({2'-[(4-{(tert-butoxycarbonyl)[2-(2-pyridinyl)ethyl]amino}anilino)carbonyl]-1,1'-biphenyl-4-yl}oxy)acetic acid

There total 1 articles about ({2'-[(4-{(tert-butoxycarbonyl)[2-(2-pyridinyl)ethyl]amino}anilino)carbonyl]-1,1'-biphenyl-4-yl}oxy)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

aqueous lithium hydroxide + ethyl ({2'-[(4-{(tert-butoxycarbonyl)[2-(2-pyridinyl)ethyl]amino}anilino)carbonyl]-1,1'-biphenyl-4-yl)oxy)acetate (408366-76-7) → ({2'-[(4-{(tert-butoxycarbonyl)[2-(2-pyridinyl)ethyl]amino}anilino)carbonyl]-1,1'-biphenyl-4-yl}oxy)acetic acid (408366-80-3)

Guidance literature:

In Tetrahydrofurfuryl alcohol;

Reference yield:

HOBt.H2O + WSC.HCl + ({2'-[(4-{(tert-butoxycarbonyl)[2-(2-pyridinyl)ethyl]amino}anilino)carbonyl]-1,1'-biphenyl-4-yl}oxy)acetic acid (408366-80-3) → 4-(2-amino-2-oxoethoxy)-2'-[(4-{(tert-butoxycarbonyl)[2-(2-pyridinyl)ethyl]amino}anilino)carbonyl]-1,1'-biphenyl (408366-81-4)

Guidance literature:

With ammonium hydroxide; In dichloromethane;

Reference yield:

({2'-[(4-{(tert-butoxycarbonyl)[2-(2-pyridinyl)ethyl]amino}anilino)carbonyl]-1,1'-biphenyl-4-yl}oxy)acetic acid (408366-80-3) → 4-(2-Anilino-2-oxoethoxy)-2'-[(4-{(tert-butoxycarbonyl)[2-(2-pyridinyl)ethyl]amino}anilino)carbonyl]-1,1'-biphenyl (408366-85-8)

Guidance literature:

upstream raw materials:

ethyl ({2'-[(4-{(tert-butoxycarbonyl)[2-(2-pyridinyl)ethyl]amino}anilino)carbonyl]-1,1'-biphenyl-4-yl)oxy)acetate

Downstream raw materials:

4-(2-amino-2-oxoethoxy)-2'-[(4-{(tert-butoxycarbonyl)[2-(2-pyridinyl)ethyl]amino}anilino)carbonyl]-1,1'-biphenyl

2-[(4-{(tert-butoxycarbonyl)[2-(2-pyridinyl)ethyl]amino}anilino)carbonyl]-4'-[2-(methylamino)-2-oxoethoxy]-1,1'-biphenyl

4-(2-Anilino-2-oxoethoxy)-2'-[(4-{(tert-butoxycarbonyl)[2-(2-pyridinyl)ethyl]amino}anilino)carbonyl]-1,1'-biphenyl

2-[(4-{(tert-butoxycarbonyl)[2-(2-pyridinyl)ethyl]amino}anilino)carbonyl]-4'-(2-oxo-2-[(phenylsulfonyl)amino]ethoxy}-1,1'-biphenyl

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