benzyl (3S,11bS)-9,11-bis(benzyloxy)-4-oxo-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-3-ylcarbamate

Base Information

Chemical Name:benzyl (3S,11bS)-9,11-bis(benzyloxy)-4-oxo-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-3-ylcarbamate
CAS No.:949463-57-4
Molecular Formula:C₃₅H₃₄N₂O₅
Molecular Weight:562.665
Hs Code.:

Synonyms:benzyl (3S,11bS)-9,11-bis(benzyloxy)-4-oxo-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-3-ylcarbamate

Suppliers and Price of benzyl (3S,11bS)-9,11-bis(benzyloxy)-4-oxo-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-3-ylcarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of benzyl (3S,11bS)-9,11-bis(benzyloxy)-4-oxo-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-3-ylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of benzyl (3S,11bS)-9,11-bis(benzyloxy)-4-oxo-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-3-ylcarbamate

There total 5 articles about benzyl (3S,11bS)-9,11-bis(benzyloxy)-4-oxo-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-3-ylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₃₆H₃₈O₆N₂

: 949463-58-5
benzyl (3S,11bR)-9,11-bis(benzyloxy)-4-oxo-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-3-ylcarbamate

: 949463-57-4
benzyl (3S,11bS)-9,11-bis(benzyloxy)-4-oxo-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-3-ylcarbamate

Guidance literature:: With sodium hydrogencarbonate; In dichloromethane; water; at 20 ℃; for 3h;
DOI:10.1021/jo070560h

Reference yield:

: 949463-56-3
methyl (S)-2-(benzyloxycarbonylamino)-5-(3,5-bis(benzyloxy)phenethylamino)-5-oxopentanoate

: 949463-57-4
benzyl (3S,11bS)-9,11-bis(benzyloxy)-4-oxo-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-3-ylcarbamate

Guidance literature:: Multi-step reaction with 3 steps

1: POCl₃ / CHCl₃ / 3 h / 70 °C

2: sodium cyanoborohydride; acetic acid / CH₂Cl₂ / 1.5 h / 0 °C

3: 860 mg / sodium hydrogen carbonate / CH₂Cl₂; H₂O / 3 h / 20 °C

With sodium cyanoborohydride; sodium hydrogencarbonate; acetic acid; trichlorophosphate; In dichloromethane; chloroform; water; 1: Bischler-Napieralski reaction;
DOI:10.1021/jo070560h

Reference yield:

: C₃₆H₃₆O₆N₂

: 949463-57-4
benzyl (3S,11bS)-9,11-bis(benzyloxy)-4-oxo-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-3-ylcarbamate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium cyanoborohydride; acetic acid / CH₂Cl₂ / 1.5 h / 0 °C

2: 860 mg / sodium hydrogen carbonate / CH₂Cl₂; H₂O / 3 h / 20 °C

With sodium cyanoborohydride; sodium hydrogencarbonate; acetic acid; In dichloromethane; water;
DOI:10.1021/jo070560h