ethyl 2-{methyl-[2-(methyl-phenyl-thiocarbamoyl)-acetyl]-amino}-5-(methylthio)-benzoate

Base Information

• Chemical Name: ethyl 2-{methyl-[2-(methyl-phenyl-thiocarbamoyl)-acetyl]-amino}-5-(methylthio)-benzoate
• CAS No.: 485810-83-1
• Molecular Formula: C₂₁H₂₄N₂O₃S₂
• Molecular Weight: 416.565

Synonyms:ethyl 2-{methyl-[2-(methyl-phenyl-thiocarbamoyl)-acetyl]-amino}-5-(methylthio)-benzoate

Chemical Property of ethyl 2-{methyl-[2-(methyl-phenyl-thiocarbamoyl)-acetyl]-amino}-5-(methylthio)-benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 2-{methyl-[2-(methyl-phenyl-thiocarbamoyl)-acetyl]-amino}-5-(methylthio)-benzoate

There total 2 articles about ethyl 2-{methyl-[2-(methyl-phenyl-thiocarbamoyl)-acetyl]-amino}-5-(methylthio)-benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

N-methyl-N-phenylthiocarbamoylacetic acid (172896-85-4) + 2-methylamino-5-methylsulfanyl-benzoic acid ethyl ester → ethyl 2-{methyl-[2-(methyl-phenyl-thiocarbamoyl)-acetyl]-amino}-5-(methylthio)-benzoate (485810-83-1)

Guidance literature:

With pyridine; 4 A molecular sieve; pivaloyl chloride; In dichloromethane; at -20 - 20 ℃; Further Variations:; Reagents; Product distribution;

DOI:10.1002/jhet.5570390427

Reference yield: 31.0%

N-methyl-N-phenylthiocarbamoylacetic acid (172896-85-4) + 2-methylamino-5-methylsulfanyl-benzoic acid ethyl ester → N-methyl-N-phenylthioacetamide (5310-07-6) + N-methyl-2-(methyl-phenyl-thiocarbamoyl)-N-phenyl-acetamide + ethyl 2-{methyl-[2-(methyl-phenyl-thiocarbamoyl)-acetyl]-amino}-5-(methylthio)-benzoate (485810-83-1)

Guidance literature:

With dicyclohexyl-carbodiimide;

DOI:10.1002/jhet.5570390427

Reference yield: 98.0%

ethyl 2-{methyl-[2-(methyl-phenyl-thiocarbamoyl)-acetyl]-amino}-5-(methylthio)-benzoate (485810-83-1) → 4-hydroxy-N,1-dimethyl-6-(methylthio)-2-oxo-N-phenyl-1,2-dihydro-3-quinolinecarbothioamide

Guidance literature:

With sodium ethanolate; In ethanol; at 5 ℃; for 0.5h;

DOI:10.1002/jhet.5570390427

upstream raw materials:

N-methyl-N-phenylthiocarbamoylacetic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 485810-83-1 ethyl 2-{methyl-[2-(methyl-phenyl-thiocarbamoyl)-acetyl]-amino}-5-(methylthio)-benzoate

Send

Send

Metric Ton KG G Pound L ML

Send

Send