2-[4-(4-Chlorophenyl)piperazin-1-yl]ethan-1-amine

Base Information

Chemical Name:2-[4-(4-Chlorophenyl)piperazin-1-yl]ethan-1-amine
CAS No.:40255-46-7
Molecular Formula:C12H18 Cl N3
Molecular Weight:239.748
Hs Code.:2933599090
DSSTox Substance ID:DTXSID50363576
Wikidata:Q82147307
Mol file:40255-46-7.mol

Synonyms:40255-46-7;2-[4-(4-chlorophenyl)piperazin-1-yl]ethan-1-amine;2-[4-(4-chlorophenyl)piperazin-1-yl]ethanamine;4-(4-CHLOROPHENYL)-1-PIPERAZINEETHANAMINE;2-(4-(4-Chlorophenyl)piperazin-1-yl)ethan-1-amine;SCHEMBL4400393;(s)-(+)-3-hydroxyquinuclidine;DTXSID50363576;AKOS005169845;AB14801;CS-0299877;FT-0656421;EN300-110811;2-[4-(4-chlorophenyl)piperazin-1-yl]ethylamine;A825013;F2187-2199

Suppliers and Price of 2-[4-(4-Chlorophenyl)piperazin-1-yl]ethan-1-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4-(4-CHLOROPHENYL)-1-PIPERAZINEETHANAMINE 95.00%
5G
$ 909.56

Total 3 raw suppliers

Chemical Property of 2-[4-(4-Chlorophenyl)piperazin-1-yl]ethan-1-amine

Chemical Property:

Vapor Pressure:5.96E-06mmHg at 25°C
Refractive Index:1.572
Boiling Point:379.2°Cat760mmHg
Flash Point:183.1°C
PSA：32.50000
Density:1.163g/cm³
LogP:2.12390
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:239.1189253
Heavy Atom Count:16
Complexity:196

Purity/Quality:

97% ^*data from raw suppliers

4-(4-CHLOROPHENYL)-1-PIPERAZINEETHANAMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CN(CCN1CCN)C2=CC=C(C=C2)Cl

Technology Process of 2-[4-(4-Chlorophenyl)piperazin-1-yl]ethan-1-amine

There total 4 articles about 2-[4-(4-Chlorophenyl)piperazin-1-yl]ethan-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 75000-30-5
2-(2-(4-(4-chlorophenyl)piperazin-1-yl)ethyl)isoindoline-1,3-dione

: 40255-46-7
2-(4-(4-chlorophenyl)-piperazin-1-yl)-ethanamine

Guidance literature:: With hydrazine; In ethanol; for 2h; Reflux;
DOI:10.1002/anie.201701905

Reference yield:

: 38212-33-8
4-(4-chlorophenyl) piperazine

: 40255-46-7
2-(4-(4-chlorophenyl)-piperazin-1-yl)-ethanamine

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / hexamethylphosphoric acid triamide / Ambient temperature

2: 30percent HBr / acetic acid / 1 h / Ambient temperature

With hydrogen bromide; potassium carbonate; In N,N,N,N,N,N-hexamethylphosphoric triamide; acetic acid;
DOI:10.1016/S0968-0896(98)00039-X