trans-2-Ethinylcyclohexanol

Base Information

• Chemical Name: trans-2-Ethinylcyclohexanol
• CAS No.: 612040-77-4
• Molecular Formula: C₈H₁₂O
• Molecular Weight: 124.183
• Mol file: 612040-77-4.mol

Synonyms:trans-2-Ethinylcyclohexanol

Chemical Property of trans-2-Ethinylcyclohexanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-2-Ethinylcyclohexanol

There total 2 articles about trans-2-Ethinylcyclohexanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

vinyl acetate (108-05-4,9003-20-7) + trans-2-ethynylcyclohexan-1-ol (55506-28-0) → trans-2-Ethinyl-cyclohexanol (134108-74-0) + trans-2-Ethinylcyclohexanol (612040-77-4) + Acetic acid (1R,2S)-2-ethynyl-cyclohexyl ester

Guidance literature:

With 4 A molecular sieve; Lipase PS (Amano); In toluene; at 30 ℃; for 12h;

DOI:10.1016/S0040-4039(03)01514-4

Reference yield:

→ trans-2-Ethinylcyclohexanol (612040-77-4)

Guidance literature:

Cyclohexenoxid 1 (n=4), /BRN= 124191///BRN= 3600393/ (aus Me3Al2Cl3 + /BRN= 3587232/), Toluol (s. Tab.);

DOI:10.1039/C39760000907

Reference yield:

trans-2-Ethinylcyclohexanol (612040-77-4) + acetic anhydride (108-24-7) → Acetic acid (1S,2R)-2-ethynyl-cyclohexyl ester

Guidance literature:

With dmap; In acetonitrile;

DOI:10.1016/S0040-4039(03)01514-4

upstream raw materials:

vinyl acetate

trans-2-ethynylcyclohexan-1-ol

Refernces