1,2-Bis(3-methoxybenzylidene)hydrazine

Base Information

Chemical Name:1,2-Bis(3-methoxybenzylidene)hydrazine
CAS No.:40252-74-2
Molecular Formula:C₁₆H₁₆N₂O₂
Molecular Weight:268.315
Hs Code.:
European Community (EC) Number:637-036-7
Nikkaji Number:J2.128.121B
Wikipedia:DMeOB
Wikidata:Q5205668
Mol file:40252-74-2.mol

Synonyms:DMeOB;1,2-Bis(3-methoxybenzylidene)hydrazine;40252-74-2;PD041254;Q5205668;{4-[(tert-Butoxycarbonyl)amino]pyridin-3-yl} boronic acid;Benzaldehyde, 3-methoxy-, ((3-methoxyphenyl)methylene)hydrazone

Suppliers and Price of 1,2-Bis(3-methoxybenzylidene)hydrazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
DMeOB
10mg
$ 353.00

TRC
DMEOB
10mg
$ 55.00

Sigma-Aldrich
DMeOB ≥98% (HPLC), solid
10mg
$ 80.50

Sigma-Aldrich
DMeOB ≥98% (HPLC), solid
50mg
$ 321.00

Aronis compounds
bis(3-methoxybenzylidene)hydrazine
20mg
$ 30.00

ApexBio Technology
DMeOB
10mg
$ 119.00

ApexBio Technology
DMeOB
50mg
$ 497.00

American Custom Chemicals Corporation
DMEOB 95.00%
10MG
$ 629.42

American Custom Chemicals Corporation
DMEOB 95.00%
50MG
$ 915.63

AHH
[(3-Methoxyphenyl)methylene]hydrazone-3methoxybenzaldehyde 98%
0.25g
$ 646.00

Total 10 raw suppliers

Chemical Property of 1,2-Bis(3-methoxybenzylidene)hydrazine

Chemical Property:

Boiling Point:438.2°Cat760mmHg
Flash Point:176.1°C
PSA：43.18000
Density:1.05g/cm³
LogP:3.15680
Storage Temp.:2-8°C
Solubility.:H2O: insoluble
XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:268.121177757
Heavy Atom Count:20
Complexity:298

Purity/Quality:

98%,99%, ^*data from raw suppliers

DMeOB ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi,N
Statements: 41-50/53
Safety Statements: 26-36/37/39-60-61

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:COC1=CC=CC(=C1)C=NN=CC2=CC(=CC=C2)OC
Isomeric SMILES:COC1=CC=CC(=C1)/C=N\N=C/C2=CC(=CC=C2)OC
Uses DMEOB is a negative allosteric modulator at mGluR-5 (1). These mGlu receptors maintain a modulatory role and act as drug targets for various neurological disorders including depression, schizophrenia and Parkinson’s.

Technology Process of 1,2-Bis(3-methoxybenzylidene)hydrazine

There total 4 articles about 1,2-Bis(3-methoxybenzylidene)hydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 6971-51-3
3-methoxybenzyl alcohol

: 40252-74-2,41097-48-7
3-methoxybenzaldehyde azine

Guidance literature:: With hydrazine hydrate; [RuHCl(CO)(2,6-bis[(di-tertbutylphosphino)methyl]pyridine)]; In toluene; at 130 ℃; for 67h; Molecular sieve; Reflux; Schlenk technique;
DOI:10.1021/acscatal.6b02946

Reference yield:

: 591-31-1
3-methoxy-benzaldehyde

: 40252-74-2,41097-48-7
3-methoxybenzaldehyde azine

Guidance literature:: With potassium hydroxide; mercury(II) oxide; Yield given. Multistep reaction; 1.) ether, room temp., 1 h; 2.) 0 deg C, 0.5 h;
DOI:10.1016/0584-8539(83)80080-4