(3S)-anti-2-n-Nuty-3-heptan-1-ol

Base Information

• Chemical Name: (3S)-anti-2-n-Nuty-3-heptan-1-ol
• CAS No.: 150062-27-4
• Molecular Formula: C₂₆H₃₉NO₄S
• Molecular Weight: 461.666
• Mol file: 150062-27-4.mol

Synonyms:(3S)-anti-2-n-Nuty-3-heptan-1-ol

Chemical Property of (3S)-anti-2-n-Nuty-3-heptan-1-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (3S)-anti-2-n-Nuty-3-heptan-1-ol

There total 2 articles about (3S)-anti-2-n-Nuty-3-heptan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-methoxybenzyl chloride (824-94-2) → (3S)-anti-2-n-Nuty-3-heptan-1-ol (150062-27-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / K₂CO₃ / Bu₄NI / acetone / 10 h / Heating

2: 1.) BH₃*THF, 2.) 3M NaOH, 30percent H₂O₂ / 1.) THF, -78 deg C, 2 h; -26 deg C, 24 h, 2.) EtOH, 25 deg C, 10 h

With sodium hydroxide; borane-THF; dihydrogen peroxide; potassium carbonate; tetra-(n-butyl)ammonium iodide; In acetone;

DOI:10.1021/jo00069a052

Reference yield:

(3S)-3--2-n-butyl-hept-1-ene (150062-23-0) → (3S)-syn-2-n-Nuty-3-heptan-1-ol (150062-28-5) + (3S)-anti-2-n-Nuty-3-heptan-1-ol (150062-27-4)

Guidance literature:

With sodium hydroxide; 9-borabicyclo[3.3.1]nonane dimer; dihydrogen peroxide; Yield given. Multistep reaction. Yields of byproduct given; 1.) THF, 25 deg C, 22 h, 2.) EtOH, 25 deg C, 6 h;

DOI:10.1021/jo00069a052

Reference yield: 70.0%

(3S)-anti-2-n-Nuty-3-heptan-1-ol (150062-27-4) → (3S)-anti-2-n-Butyl-3-(N-tosylamino)heptan-1-ol (150062-29-6)

Guidance literature:

With ammonium cerium(IV) nitrate; In water; acetonitrile; at 25 ℃; for 0.166667h;

DOI:10.1021/jo00069a052

upstream raw materials:

(3S)-3--2-n-butyl-hept-1-ene

p-methoxybenzyl chloride

Downstream raw materials:

(3S)-anti-2-n-Butyl-3-(N-tosylamino)heptan-1-ol