3-(3-Methoxybenzoyl)adipic acid

Base Information

• Chemical Name: 3-(3-Methoxybenzoyl)adipic acid
• CAS No.: 17797-68-1
• Molecular Formula: C₁₄H₁₆O₆
• Molecular Weight: 280.277
• European Community (EC) Number: 663-122-9
• Mol file: 17797-68-1.mol

Synonyms:3-(3-METHOXYBENZOYL)ADIPIC ACID;SCHEMBL7823664;AKOS024341058

Chemical Property of 3-(3-Methoxybenzoyl)adipic acid

Chemical Property:

• XLogP3: 0.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 8
• Exact Mass: 280.09468823
• Heavy Atom Count: 20
• Complexity: 365

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=CC=CC(=C1)C(=O)C(CCC(=O)O)CC(=O)O

Technology Process of 3-(3-Methoxybenzoyl)adipic acid

There total 5 articles about 3-(3-Methoxybenzoyl)adipic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

β-Carboxy-β-<3-methoxy-benzoyl>-adipinsaeure-trimethylester (17797-66-9) → β-(3-Methoxybenzoyl)-adipinsaeure (17797-68-1)

Guidance literature:

With sulfuric acid; acetic acid; Heating;

DOI:10.1021/ja01004a041

Reference yield:

methyl 3-methoxybenzoate (5368-81-0) → β-(3-Methoxybenzoyl)-adipinsaeure (17797-68-1)

Guidance literature:

Multi-step reaction with 3 steps

1: NaH

2: NaH

3: aq. H₂SO₄, AcOH / Heating

With sulfuric acid; sodium hydride; acetic acid;

DOI:10.1021/ja01004a041

Reference yield:

α-(3-Methoxybenzoyl)-glutarsaeure-dimethylester (17797-67-0) → β-(3-Methoxybenzoyl)-adipinsaeure (17797-68-1)

Guidance literature:

Multi-step reaction with 2 steps

1: NaH

2: aq. H₂SO₄, AcOH / Heating

With sulfuric acid; sodium hydride; acetic acid;

DOI:10.1021/ja01004a041

upstream raw materials:

β-Carboxy-β-<3-methoxy-benzoyl>-adipinsaeure-trimethylester

4α-(3-Methoxybenzoyl)-bernteinsaeure-dimethylester

acrylic acid methyl ester

methyl 3-methoxybenzoate

Downstream raw materials:

β-(3-Methoxybenzoyl)-adipinsaeure-dimethylester

β-(3-Methoxybenzyl)-adipinsaeure

β-(3-Methoxybenzyl)-adipinsaeure-dimethylester

2-(2-Carbomethoxyethyl)-5-methoxy-8-chlor-4-tetralon