(S)-3-((tert-Butoxycarbonyl)amino)-2-methoxypropanoic acid

Base Information

Chemical Name:(S)-3-((tert-Butoxycarbonyl)amino)-2-methoxypropanoic acid
CAS No.:412352-66-0
Molecular Formula:C₉H₁₇NO₅
Molecular Weight:219.238
Hs Code.:
European Community (EC) Number:826-664-9
Wikidata:Q76511779
Mol file:412352-66-0.mol

Synonyms:412352-66-0;(S)-3-((tert-Butoxycarbonyl)amino)-2-methoxypropanoic acid;(2S)-2-methoxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid;SCHEMBL7403513;MFCD18831547;AKOS022191393;AS-32948;DB-310410;EN300-383782;Z1505715755;(S)-3-((tert-Butoxycarbonyl)amino)-2-methoxypropanoicacid;(2S)-3-{[(tert-butoxy)carbonyl]amino}-2-methoxypropanoic acid;(2S)-3-[(TERT-BUTOXYCARBONYL)AMINO]-2-METHOXYPROPANOIC ACID;(2S)-2-Methoxy-3-({[(2-Methyl-2-Propanyl)Oxy]Carbonyl}Amino)Propanoic Acid

Suppliers and Price of (S)-3-((tert-Butoxycarbonyl)amino)-2-methoxypropanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-3-((tert-Butoxycarbonyl)amino)-2-methoxypropanoicacid 95+%
5g
$ 1716.00

Crysdot
(S)-3-((tert-Butoxycarbonyl)amino)-2-methoxypropanoicacid 95+%
1g
$ 570.00

Chemenu
(S)-3-((tert-Butoxycarbonyl)amino)-2-methoxypropanoicacid 95%
1g
$ 539.00

AK Scientific
(S)-3-((Tert-Butoxycarbonyl)amino)-2-methoxypropanoicacid
10g
$ 4492.00

Total 2 raw suppliers

Chemical Property of (S)-3-((tert-Butoxycarbonyl)amino)-2-methoxypropanoic acid

Chemical Property:

PSA：84.86000
LogP:1.00160
XLogP3:0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:219.11067264
Heavy Atom Count:15
Complexity:233

Purity/Quality:

98% ^*data from raw suppliers

(S)-3-((tert-Butoxycarbonyl)amino)-2-methoxypropanoicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NCC(C(=O)O)OC
Isomeric SMILES:CC(C)(C)OC(=O)NC[C@@H](C(=O)O)OC

Technology Process of (S)-3-((tert-Butoxycarbonyl)amino)-2-methoxypropanoic acid

There total 4 articles about (S)-3-((tert-Butoxycarbonyl)amino)-2-methoxypropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: (2S)‐3‐{[(tert‐butoxy)carbonyl]amino}‐2‐methoxypropanoic acid methyl ester

: 412352-66-0,412352-67-1
(2S)‐3‐{[(tert‐butoxy)carbonyl]amino}‐2‐methoxypropanoic acid

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; at 20 ℃; for 2h;

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 412352-66-0,412352-67-1
(2S)‐3‐{[(tert‐butoxy)carbonyl]amino}‐2‐methoxypropanoic acid

Guidance literature:: Multi-step reaction with 4 steps

1: sodium hydroxide / tetrahydrofuran; water / 9 h / 20 °C

2: diazomethyl-trimethyl-silane / hexane; dichloromethane / 0.5 h / 0 - 20 °C

3: silver(l) oxide / acetonitrile / 13 h / 70 °C

4: sodium hydroxide / tetrahydrofuran / 2 h / 20 °C

With sodium hydroxide; silver(l) oxide; diazomethyl-trimethyl-silane; In tetrahydrofuran; hexane; dichloromethane; water; acetonitrile;

Reference yield:

: 52558-24-4
(s)-3-tert-butoxycarbonylamino-2-hydroxypropionic acid

: 412352-66-0,412352-67-1
(2S)‐3‐{[(tert‐butoxy)carbonyl]amino}‐2‐methoxypropanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: diazomethyl-trimethyl-silane / hexane; dichloromethane / 0.5 h / 0 - 20 °C

2: silver(l) oxide / acetonitrile / 13 h / 70 °C

3: sodium hydroxide / tetrahydrofuran / 2 h / 20 °C

With sodium hydroxide; silver(l) oxide; diazomethyl-trimethyl-silane; In tetrahydrofuran; hexane; dichloromethane; acetonitrile;