acetic acid 3,4,5-triacetoxy-6-phrnylsulfanyl-tetrahydropyran-2-ylmethyl ester

Base Information

Chemical Name:acetic acid 3,4,5-triacetoxy-6-phrnylsulfanyl-tetrahydropyran-2-ylmethyl ester
CAS No.:943226-48-0
Molecular Formula:C₂₀H₂₄O₉S
Molecular Weight:440.471
Hs Code.:

Synonyms:acetic acid 3,4,5-triacetoxy-6-phrnylsulfanyl-tetrahydropyran-2-ylmethyl ester

Suppliers and Price of acetic acid 3,4,5-triacetoxy-6-phrnylsulfanyl-tetrahydropyran-2-ylmethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of acetic acid 3,4,5-triacetoxy-6-phrnylsulfanyl-tetrahydropyran-2-ylmethyl ester

Chemical Property:

Purity/Quality:: 95% ^*data from raw suppliers

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Technology Process of acetic acid 3,4,5-triacetoxy-6-phrnylsulfanyl-tetrahydropyran-2-ylmethyl ester

There total 1 articles about acetic acid 3,4,5-triacetoxy-6-phrnylsulfanyl-tetrahydropyran-2-ylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 108-98-5
thiophenol

: 188783-40-6
α/β‐L‐glucopyranosyl‐1,2,3,4,5‐pentaacetate

: 943226-48-0
acetic acid 3,4,5-triacetoxy-6-phrnylsulfanyl-tetrahydropyran-2-ylmethyl ester

Guidance literature:: With boron trifluoride diethyl etherate; In dichloromethane; at 20 ℃;
DOI:10.1021/ol0707970

Reference yield:

: 943226-48-0
acetic acid 3,4,5-triacetoxy-6-phrnylsulfanyl-tetrahydropyran-2-ylmethyl ester

: C₄₆H₇₆O₇Si

Guidance literature:: Multi-step reaction with 25 steps

1.1: NaOMe / methanol; CH₂Cl₂ / 3.5 h / 0 °C

2.1: 78 percent / pyridine / dimethylformamide / -40 °C

3.1: 90 percent / KOBu-t / tetrahydrofuran / 0.5 h / 0 °C

4.1: 77 percent / lithium naphthalenide / tetrahydrofuran / -78 - -10 °C

5.1: 89 percent / imidazole / dimethylformamide / 12 h / 20 °C

6.1: t-BuLi / tetrahydrofuran; pentane / 0.5 h / -78 °C

6.2: 100 percent / tetrahydrofuran; pentane / -78 - 20 °C

7.1: 96 percent / dimethyl dioxirane / CH₂Cl₂; diethyl ether / 0.25 h / -78 °C

8.1: 100 percent / NaH / hexamethylphosphoric acid triamide / 0.83 h / 0 °C

9.1: 96 percent / iPr₂NEt / CH₂Cl₂ / -78 °C

10.1: 92 percent / DCC; DMAP / CH₂Cl₂ / 0 - 20 °C

11.1: 91 percent / 10-camphorsulfonic acid / methanol / 0.08 h / 0 °C

12.1: NaH / 4 h / 20 °C

12.2: 0.5 h / 20 °C

13.1: 0.046 g / n-Bu₃SnH; AIBN / benzene / 1.5 h / Heating

14.1: 100 percent / TiCl₄; TMEDA; Zn dust / PbCl₂ / CH₂Cl₂; tetrahydrofuran / 2 h

15.1: 0.038 g / Grubbs second generation catalyst / benzene / 36 h / Heating

16.1: dimethyl dioxirane / CH₂Cl₂; acetone / -78 - 0 °C

16.2: 95 percent / DIBAL / CH₂Cl₂; hexane / 2 h / -78 °C

17.1: 80 percent / PPTS; pyridine / chlorobenzene / 48 h / Heating

18.1: 76 percent / H₂ / PtO₂*H₂O / hexane; ethyl acetate / 5.5 h / 760.05 Torr

19.1: 94 percent / HF*pyridine / tetrahydrofuran / 1 h / 0 °C

20.1: CH₂Cl₂ / 0.25 h / -78 °C

20.2: 2,6-lutidine / CH₂Cl₂ / 0.5 h / 20 °C

21.1: CuI / tetrahydrofuran / -78 - 0 °C

21.2: tetrahydrofuran / 2 h / -40 °C

22.1: 0.0016 g / 10-camphorsulfonic acid / methanol / 1 h / 0 °C

23.1: 2,4,6-trichlorobenzoyl chloride; NEt₃ / tetrahydrofuran / 2 h / 40 °C

23.2: 69 percent / DMAP / toluene / 2 h / 40 °C

24.1: 100 percent / TiCl₄; TMEDA; Zn / PbCl₂ / CH₂Cl₂ / 65 °C

25.1: Schrock Mo catalyst / hexane / 60 °C

With pyridine; 1H-imidazole; dmap; copper(l) iodide; 2,2'-azobis(isobutyronitrile); N,N,N,N,-tetramethylethylenediamine; 2,4,6-trichlorobenzoyl chloride; (1S)-10-camphorsulfonic acid; potassium tert-butylate; hydrogen; tert.-butyl lithium; tri-n-butyl-tin hydride; sodium methylate; 3,3-dimethyldioxirane; pyridinium p-toluenesulfonate; titanium tetrachloride; sodium hydride; pyridine hydrogenfluoride; triethylamine; N-ethyl-N,N-diisopropylamine; naphthalen-1-yl-lithium; dicyclohexyl-carbodiimide; zinc; tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; platinum(IV) oxide; lead(II) chloride; In tetrahydrofuran; methanol; N,N,N,N,N,N-hexamethylphosphoric triamide; diethyl ether; hexane; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; chlorobenzene; acetone; pentane; benzene;
DOI:10.1021/ol0707970