(7,8-dihydro[1,4]dioxino[2,3-g]quinazolin-4-yl)-(3'-methansulfonamidopheyl)amine hydrochloride

Base Information

Chemical Name:(7,8-dihydro[1,4]dioxino[2,3-g]quinazolin-4-yl)-(3'-methansulfonamidopheyl)amine hydrochloride
CAS No.:1456819-61-6
Molecular Formula:C₁₇H₁₆N₄O₄S*ClH
Molecular Weight:408.865
Hs Code.:

Synonyms:(7,8-dihydro[1,4]dioxino[2,3-g]quinazolin-4-yl)-(3'-methansulfonamidopheyl)amine hydrochloride

Suppliers and Price of (7,8-dihydro[1,4]dioxino[2,3-g]quinazolin-4-yl)-(3'-methansulfonamidopheyl)amine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (7,8-dihydro[1,4]dioxino[2,3-g]quinazolin-4-yl)-(3'-methansulfonamidopheyl)amine hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (7,8-dihydro[1,4]dioxino[2,3-g]quinazolin-4-yl)-(3'-methansulfonamidopheyl)amine hydrochloride

There total 5 articles about (7,8-dihydro[1,4]dioxino[2,3-g]quinazolin-4-yl)-(3'-methansulfonamidopheyl)amine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 37045-73-1
3-(methylsulfonamido)aniline

: 52791-05-6
4-chloro-7,8-dihydro[1,4]-dioxino[2,3-g]quinazoline

: 1456819-61-6
(7,8-dihydro[1,4]dioxino[2,3-g]quinazolin-4-yl)-(3'-methansulfonamidopheyl)amine hydrochloride

Guidance literature:: In isopropyl alcohol; at 80 ℃; for 0.25h; Microwave irradiation;
DOI:10.1016/j.ejmech.2013.06.057

Reference yield:

: ethyl N-(2,3-dihydro-1,4-benzodioxin-6-yl)carbamate

: 1456819-61-6
(7,8-dihydro[1,4]dioxino[2,3-g]quinazolin-4-yl)-(3'-methansulfonamidopheyl)amine hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1.1: trifluoroacetic acid / 0.17 h / 110 °C / Microwave irradiation

1.2: 4 h / Reflux

2.1: acetic acid; ammonium cerium (IV) nitrate / water / 0.08 h / 20 °C

3.1: triethylamine; trichlorophosphate / 3 h / Reflux

4.1: isopropyl alcohol / 0.25 h / 80 °C / Microwave irradiation

With ammonium cerium (IV) nitrate; acetic acid; triethylamine; trifluoroacetic acid; trichlorophosphate; In water; isopropyl alcohol;
DOI:10.1016/j.ejmech.2013.06.057

Reference yield:

: 1207868-16-3
7,8-dihydro[1,4]dioxino[2,3-g]quinazoline

: 1456819-61-6
(7,8-dihydro[1,4]dioxino[2,3-g]quinazolin-4-yl)-(3'-methansulfonamidopheyl)amine hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: acetic acid; ammonium cerium (IV) nitrate / water / 0.08 h / 20 °C

2: triethylamine; trichlorophosphate / 3 h / Reflux

3: isopropyl alcohol / 0.25 h / 80 °C / Microwave irradiation

With ammonium cerium (IV) nitrate; acetic acid; triethylamine; trichlorophosphate; In water; isopropyl alcohol;
DOI:10.1016/j.ejmech.2013.06.057