4-(4-(dimethylamino)phenyl)-1-phenyl-3-(pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridine-6-carboxylic acid

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Chemical Name:4-(4-(dimethylamino)phenyl)-1-phenyl-3-(pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridine-6-carboxylic acid
CAS No.:1357585-68-2
Molecular Formula:C₂₆H₂₁N₅O₂
Molecular Weight:435.485
Hs Code.:

Synonyms:4-(4-(dimethylamino)phenyl)-1-phenyl-3-(pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridine-6-carboxylic acid

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Chemical Property of 4-(4-(dimethylamino)phenyl)-1-phenyl-3-(pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridine-6-carboxylic acid

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Technology Process of 4-(4-(dimethylamino)phenyl)-1-phenyl-3-(pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridine-6-carboxylic acid

There total 3 articles about 4-(4-(dimethylamino)phenyl)-1-phenyl-3-(pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridine-6-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1152711-48-2
5-amino-1-phenyl-3-(pyridin-3-yl)-1H-pyrazole

: 127-17-3
2-oxo-propionic acid

: 100-10-7
4-dimethylamino-benzaldehyde

: 1357585-68-2
4-(4-(dimethylamino)phenyl)-1-phenyl-3-(pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridine-6-carboxylic acid

Guidance literature:: With acetic acid; at 160 ℃; for 0.416667h; Microwave irradiation;
DOI:10.1016/j.ejmech.2011.11.038

Reference yield:

: 614-18-6
3-pyridinecarboxylic acid ethyl ester

: 1357585-68-2
4-(4-(dimethylamino)phenyl)-1-phenyl-3-(pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridine-6-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydride

2: methanesulfonic acid / ethanol / 8 h / Reflux

3: acetic acid / 0.42 h / 160 °C / Microwave irradiation

With methanesulfonic acid; sodium hydride; acetic acid; In ethanol;
DOI:10.1016/j.ejmech.2011.11.038

Reference yield:

: 30510-18-0
nicotinoylacetonitrile

: 1357585-68-2
4-(4-(dimethylamino)phenyl)-1-phenyl-3-(pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridine-6-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: methanesulfonic acid / ethanol / 8 h / Reflux

2: acetic acid / 0.42 h / 160 °C / Microwave irradiation

With methanesulfonic acid; acetic acid; In ethanol;
DOI:10.1016/j.ejmech.2011.11.038