1,1-dimethylsilinan-4-amine hydrochloride

Base Information

• Chemical Name: 1,1-dimethylsilinan-4-amine hydrochloride
• CAS No.: 1330166-71-6
• Molecular Formula: C₇H₁₇NSi*ClH
• Molecular Weight: 179.765
• Mol file: 1330166-71-6.mol

Synonyms:1,1-dimethylsilinan-4-amine hydrochloride

Chemical Property of 1,1-dimethylsilinan-4-amine hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,1-dimethylsilinan-4-amine hydrochloride

There total 4 articles about 1,1-dimethylsilinan-4-amine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C7H15NOSi → 1,1-dimethylsilinan-4-amine hydrochloride (1330166-71-6)

Guidance literature:

C₇H₁₅NOSi; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 4h; Inert atmosphere; Reflux;

With hydrogenchloride; In 1,4-dioxane; Inert atmosphere;

DOI:10.1021/ja2050666

Reference yield:

1,1-dimethyl-1-silacyclohexan-4-one (18276-42-1) → 1,1-dimethylsilinan-4-amine hydrochloride (1330166-71-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: hydroxylamine hydrochloride; sodium acetate / ethanol; water / 2 h / Reflux; Inert atmosphere

2.1: lithium aluminium tetrahydride / tetrahydrofuran / 4 h / 0 °C / Inert atmosphere; Reflux

2.2: Inert atmosphere

With lithium aluminium tetrahydride; hydroxylamine hydrochloride; sodium acetate; In tetrahydrofuran; ethanol; water;

DOI:10.1021/ja2050666

Reference yield:

divinyldimethylsilane (10519-87-6) → 1,1-dimethylsilinan-4-amine hydrochloride (1330166-71-6)

Guidance literature:

Multi-step reaction with 4 steps

1.1: 9-borabicyclo[3.3.1]nonane dimer / hexane / 2 h / Reflux; Inert atmosphere

1.2: 1 h / 20 °C / Inert atmosphere; Reflux

1.3: 20 °C / Inert atmosphere

2.1: lithium tert-butoxide / tetrahydrofuran / 0.5 h / 0 - 20 °C / Inert atmosphere

2.2: 3 h / Reflux

3.1: hydroxylamine hydrochloride; sodium acetate / ethanol; water / 2 h / Reflux; Inert atmosphere

4.1: lithium aluminium tetrahydride / tetrahydrofuran / 4 h / 0 °C / Inert atmosphere; Reflux

4.2: Inert atmosphere

With lithium aluminium tetrahydride; 9-borabicyclo[3.3.1]nonane dimer; hydroxylamine hydrochloride; sodium acetate; lithium tert-butoxide; In tetrahydrofuran; ethanol; hexane; water;

DOI:10.1021/ja2050666

upstream raw materials:

1,1-dimethyl-1-silacyclohexan-4-one

divinyldimethylsilane

4-methoxy-1,1-dimethyl-1-sila-4-boracyclohexane

Refernces