C₃₆H₅₁FN₂O₅Si₂

Base Information

Chemical Name:C₃₆H₅₁FN₂O₅Si₂
CAS No.:1445396-36-0
Molecular Formula:C₃₆H₅₁FN₂O₅Si₂
Molecular Weight:666.981
Hs Code.:

C<sub>36</sub>H<sub>51</sub>FN<sub>2</sub>O<sub>5</sub>Si<sub>2</sub>

Synonyms:C₃₆H₅₁FN₂O₅Si₂

Suppliers and Price of C₃₆H₅₁FN₂O₅Si₂

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of C₃₆H₅₁FN₂O₅Si₂

Chemical Property:

Purity/Quality:: 97% ^*data from raw suppliers

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Technology Process of C₃₆H₅₁FN₂O₅Si₂

There total 8 articles about C₃₆H₅₁FN₂O₅Si₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.4%

: 1445379-66-7
C₃₂H₄₃FN₂O₆Si₂

: bromo(isobutyl)triphenylphosphorane

: 1445396-36-0
C₃₆H₅₁FN₂O₅Si₂

Guidance literature:: bromo(isobutyl)triphenylphosphorane; With potassium tert-butylate; In tetrahydrofuran; at 0 - 20 ℃; for 1h; Inert atmosphere;

C₃₂H₄₃FN₂O₆Si₂; In tetrahydrofuran; at 0 - 20 ℃; for 3h;

Reference yield:

: 56287-17-3,69123-94-0,784-71-4
2'-deoxy-2'-fluorouridine

: 1445396-36-0
C₃₆H₅₁FN₂O₅Si₂

Guidance literature:: Multi-step reaction with 7 steps

1.1: pyridine; 4,4'-dimethoxytrityl chloride / 15 h / 20 °C

1.2: 14 h / 20 °C

1.3: 15 h / 20 °C

2.1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / acetonitrile / 3 h / Reflux

3.1: sodium hydroxide / 1,4-dioxane; water / 2 h / 20 °C

3.2: 0.5 h / 20 °C / pH 7

4.1: pyridine / dichloromethane / 14 h / 0 - 20 °C

5.1: 1H-imidazole / dichloromethane / 14 h / 20 °C

5.2: 15 h / 20 °C

6.1: Dess-Martin periodane / dichloromethane / 2.5 h / 0 - 20 °C / Inert atmosphere

7.1: potassium tert-butylate / tetrahydrofuran / 1 h / 0 - 20 °C / Inert atmosphere

7.2: 3 h / 0 - 20 °C

With pyridine; 1H-imidazole; 4,4'-dimethoxytrityl chloride; potassium tert-butylate; Dess-Martin periodane; sodium hydroxide; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In tetrahydrofuran; 1,4-dioxane; dichloromethane; water; acetonitrile;

Reference yield:

: 1445379-59-8
2’-deoxy-2’-fluoro-3’-O-(tert-butyldimethylsilyl)uridine

: 1445396-36-0
C₃₆H₅₁FN₂O₅Si₂

Guidance literature:: Multi-step reaction with 6 steps

1.1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / acetonitrile / 3 h / Reflux

2.1: sodium hydroxide / 1,4-dioxane; water / 2 h / 20 °C

2.2: 0.5 h / 20 °C / pH 7

3.1: pyridine / dichloromethane / 14 h / 0 - 20 °C

4.1: 1H-imidazole / dichloromethane / 14 h / 20 °C

4.2: 15 h / 20 °C

5.1: Dess-Martin periodane / dichloromethane / 2.5 h / 0 - 20 °C / Inert atmosphere

6.1: potassium tert-butylate / tetrahydrofuran / 1 h / 0 - 20 °C / Inert atmosphere

6.2: 3 h / 0 - 20 °C

With pyridine; 1H-imidazole; potassium tert-butylate; Dess-Martin periodane; sodium hydroxide; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In tetrahydrofuran; 1,4-dioxane; dichloromethane; water; acetonitrile;