1-tert-Butyl-2,2-dichloro-5-phenyl-3,3-bis-trifluoromethyl-2,3-dihydro-1H-[1,4,2]diazasilole

Base Information

• Chemical Name: 1-tert-Butyl-2,2-dichloro-5-phenyl-3,3-bis-trifluoromethyl-2,3-dihydro-1H-[1,4,2]diazasilole
• CAS No.: 165397-27-3
• Molecular Formula: C₁₄H₁₄Cl₂F₆N₂Si
• Molecular Weight: 423.26
• Mol file: 165397-27-3.mol

Synonyms:1-tert-Butyl-2,2-dichloro-5-phenyl-3,3-bis-trifluoromethyl-2,3-dihydro-1H-[1,4,2]diazasilole

Chemical Property of 1-tert-Butyl-2,2-dichloro-5-phenyl-3,3-bis-trifluoromethyl-2,3-dihydro-1H-[1,4,2]diazasilole

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 1-tert-Butyl-2,2-dichloro-5-phenyl-3,3-bis-trifluoromethyl-2,3-dihydro-1H-[1,4,2]diazasilole

There total 1 articles about 1-tert-Butyl-2,2-dichloro-5-phenyl-3,3-bis-trifluoromethyl-2,3-dihydro-1H-[1,4,2]diazasilole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-tert-Butyl-N'-(2,2,2-trifluoro-1-trifluoromethyl-ethylidene)-benzamidine → 1-tert-Butyl-2,2-dichloro-5-phenyl-3,3-bis-trifluoromethyl-2,3-dihydro-1H-[1,4,2]diazasilole (165397-27-3)

Guidance literature:

With trichlorosilane; 1,8-diazabicyclo[5.4.0]undec-7-ene; Yield given. Multistep reaction; 1.) THF, -78 deg C, 15 min, 2.) THF, 20 deg C, 3 h;

DOI:10.1021/ja00123a022

Reference yield: 79.7%

1-tert-Butyl-2,2-dichloro-5-phenyl-3,3-bis-trifluoromethyl-2,3-dihydro-1H-[1,4,2]diazasilole (165397-27-3) → 1-tert-Butyl-5-fluoro-2-phenyl-4-trifluoromethyl-1H-imidazole

Guidance literature:

With potassium; In tetrahydrofuran; at 20 ℃; for 36h;

DOI:10.1021/ja00123a022

Reference yield:

1-tert-Butyl-2,2-dichloro-5-phenyl-3,3-bis-trifluoromethyl-2,3-dihydro-1H-[1,4,2]diazasilole (165397-27-3) → C14H16Cl2F6N2OSi

Guidance literature:

Multi-step reaction with 2 steps

1: 79.7 percent / K / tetrahydrofuran / 36 h / 20 °C

2: 59.2 percent / H₂O / toluene / 72 h / 5 °C

With water; potassium; In tetrahydrofuran; toluene;

DOI:10.1021/ja00123a022