4-(benzyloxycarbonylamino)bicyclo[2.2.1]heptane-1-carboxylic acid methyl ester

Base Information

Chemical Name:4-(benzyloxycarbonylamino)bicyclo[2.2.1]heptane-1-carboxylic acid methyl ester
CAS No.:1252672-35-7
Molecular Formula:C₁₇H₂₁NO₄
Molecular Weight:303.358
Hs Code.:

Synonyms:4-(benzyloxycarbonylamino)bicyclo[2.2.1]heptane-1-carboxylic acid methyl ester

Suppliers and Price of 4-(benzyloxycarbonylamino)bicyclo[2.2.1]heptane-1-carboxylic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 3 raw suppliers

Chemical Property of 4-(benzyloxycarbonylamino)bicyclo[2.2.1]heptane-1-carboxylic acid methyl ester

Chemical Property:

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

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Technology Process of 4-(benzyloxycarbonylamino)bicyclo[2.2.1]heptane-1-carboxylic acid methyl ester

There total 5 articles about 4-(benzyloxycarbonylamino)bicyclo[2.2.1]heptane-1-carboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 15448-77-8
4-carbomethoxybicyclo<2.2.1>heptane-1-carboxylic acid

: 100-51-6,185532-71-2
benzyl alcohol

: 1252672-35-7
4-(benzyloxycarbonylamino)bicyclo[2.2.1]heptane-1-carboxylic acid methyl ester

Guidance literature:: 4-carbomethoxybicyclo<2.2.1>heptane-1-carboxylic acid; With diphenyl phosphoryl azide; N-ethyl-N,N-diisopropylamine; In toluene; at 10 ℃; for 2h;

benzyl alcohol; In toluene; at 50 - 110 ℃;

Reference yield:

: 15448-76-7
dimethyl bicyclo<2.2.1>heptane-1,4-dicarboxylate

: 1252672-35-7
4-(benzyloxycarbonylamino)bicyclo[2.2.1]heptane-1-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: methanol; sodium hydroxide / tetrahydrofuran / 15 - 20 °C

2.1: N-ethyl-N,N-diisopropylamine; diphenyl phosphoryl azide / toluene / 2.5 h / 60 °C / Reflux

2.2: 24 h / 50 °C / Reflux

With methanol; diphenyl phosphoryl azide; N-ethyl-N,N-diisopropylamine; sodium hydroxide; In tetrahydrofuran; toluene;

Reference yield:

: 4056-78-4,826-02-8
cyclopentane-1,3-dicarboxylic acid

: 1252672-35-7
4-(benzyloxycarbonylamino)bicyclo[2.2.1]heptane-1-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 4 steps

1.1: sulfuric acid / water / 0 - 90 °C

2.1: n-butyllithium; 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; N-ethyl-N,N-diisopropylamine / tetrahydrofuran; hexane / 0.5 h / -78 - 0 °C

2.2: 12 h / 20 °C

3.1: methanol; sodium hydroxide / tetrahydrofuran / 0 - 20 °C

4.1: N-ethyl-N,N-diisopropylamine; diphenyl phosphoryl azide / toluene / 2 h / 10 °C

4.2: 50 - 110 °C

With methanol; 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; n-butyllithium; sulfuric acid; diphenyl phosphoryl azide; N-ethyl-N,N-diisopropylamine; sodium hydroxide; In tetrahydrofuran; hexane; water; toluene;