N⁶-benzoyl-2',3'-didehydro-2',3'-dideoxyadenosine

Base Information

Chemical Name:N⁶-benzoyl-2',3'-didehydro-2',3'-dideoxyadenosine
CAS No.:142068-15-3
Molecular Formula:C₁₇H₁₅N₅O₃
Molecular Weight:337.338
Hs Code.:

N<sup>6</sup>-benzoyl-2',3'-didehydro-2',3'-dideoxyadenosine

Synonyms:N⁶-benzoyl-2',3'-didehydro-2',3'-dideoxyadenosine

Suppliers and Price of N⁶-benzoyl-2',3'-didehydro-2',3'-dideoxyadenosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N⁶-benzoyl-2',3'-didehydro-2',3'-dideoxyadenosine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N⁶-benzoyl-2',3'-didehydro-2',3'-dideoxyadenosine

There total 4 articles about N⁶-benzoyl-2',3'-didehydro-2',3'-dideoxyadenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 142068-14-2
N⁶-benzoyl-5'-O-(tert-butyldimethylsilyl)-2',3'-didehydro-2',3'-dideoxyadenosine

: 142068-15-3
N⁶-benzoyl-2',3'-didehydro-2',3'-dideoxyadenosine

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; for 1h; Ambient temperature;
DOI:10.1021/jm00093a003

Reference yield:

: 69504-16-1
N⁶-benzoyl-5'-O-(tert-butyldimethylsilyl)adenosine

: 142068-15-3
N⁶-benzoyl-2',3'-didehydro-2',3'-dideoxyadenosine

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) NaH, imidazole / 1.) THF, 45 min, 2.) THF, 30 min

2: tetrahydrofuran / 0.5 h

3: 91 percent / tri-n-butyltin hydride, azobisisobutyronitrile / toluene / 1 h / Heating

4: 87 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 1 h / Ambient temperature

With 1H-imidazole; 2,2'-azobis(isobutyronitrile); tetrabutyl ammonium fluoride; tri-n-butyl-tin hydride; sodium hydride; In tetrahydrofuran; toluene;
DOI:10.1021/jm00093a003

Reference yield:

: Dithiocarbonic acid O-[(2R,3R,4R,5R)-5-(6-benzoylamino-purin-9-yl)-2-(tert-butyl-dimethyl-silanyloxymethyl)-4-dithiocarboxyoxy-tetrahydro-furan-3-yl] ester

: 142068-15-3
N⁶-benzoyl-2',3'-didehydro-2',3'-dideoxyadenosine

Guidance literature:: Multi-step reaction with 3 steps

1: tetrahydrofuran / 0.5 h

2: 91 percent / tri-n-butyltin hydride, azobisisobutyronitrile / toluene / 1 h / Heating

3: 87 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 1 h / Ambient temperature

With 2,2'-azobis(isobutyronitrile); tetrabutyl ammonium fluoride; tri-n-butyl-tin hydride; In tetrahydrofuran; toluene;
DOI:10.1021/jm00093a003