4-amino-7-(β-D-ribofuranosyl)pyrrolo<2,3-d>pyrimidine-5-carboxy-L-phenylalanine amide

Base Information

Chemical Name:4-amino-7-(β-D-ribofuranosyl)pyrrolo<2,3-d>pyrimidine-5-carboxy-L-phenylalanine amide
CAS No.:117175-52-7
Molecular Formula:C₂₁H₂₄N₆O₆
Molecular Weight:456.458
Hs Code.:

Synonyms:4-amino-7-(β-D-ribofuranosyl)pyrrolo<2,3-d>pyrimidine-5-carboxy-L-phenylalanine amide

Suppliers and Price of 4-amino-7-(β-D-ribofuranosyl)pyrrolo<2,3-d>pyrimidine-5-carboxy-L-phenylalanine amide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-amino-7-(β-D-ribofuranosyl)pyrrolo<2,3-d>pyrimidine-5-carboxy-L-phenylalanine amide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-amino-7-(β-D-ribofuranosyl)pyrrolo<2,3-d>pyrimidine-5-carboxy-L-phenylalanine amide

There total 4 articles about 4-amino-7-(β-D-ribofuranosyl)pyrrolo<2,3-d>pyrimidine-5-carboxy-L-phenylalanine amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 117175-51-6
4-amino-7-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)pyrrolo<2,3-d>pyrimidine-5-carboxy-L-phenylalanine methyl ester

: 117175-52-7
4-amino-7-(β-D-ribofuranosyl)pyrrolo<2,3-d>pyrimidine-5-carboxy-L-phenylalanine amide

Guidance literature:: With ammonia; In methanol; for 12h; Ambient temperature;
DOI:10.1016/S0040-4020(01)85882-8

Reference yield:

: 606-58-6
Vengicide

: 117175-52-7
4-amino-7-(β-D-ribofuranosyl)pyrrolo<2,3-d>pyrimidine-5-carboxy-L-phenylalanine amide

Guidance literature:: Multi-step reaction with 4 steps

1: 77 percent / 1.) 6 N KOH / 1.) reflux, 3 h; 2.) 0 deg C

2: 1-hydroxybenzotriazole monohydrate, 1-ethyl-3-<3-(dimethylamino)propyl>carbodiimide hydrochloride, triethylamine / dimethylformamide / 1.) 0 deg C, 3 h; 2.) r.t., overnight

3: dimethylformamide; pyridine

4: 84 percent / NH₃ / methanol / 12 h / Ambient temperature

With potassium hydroxide; ammonia; 1-hydroxybenzotriazol-hydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In pyridine; methanol; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)85882-8

Reference yield:

: 4-amino-7-(β-D-ribofuranosyl)pyrrolo<2,3-d>pyrimidine-5-carboxy-L-phenylalanine methyl ester

: 117175-52-7
4-amino-7-(β-D-ribofuranosyl)pyrrolo<2,3-d>pyrimidine-5-carboxy-L-phenylalanine amide

Guidance literature:: Multi-step reaction with 2 steps

1: dimethylformamide; pyridine

2: 84 percent / NH₃ / methanol / 12 h / Ambient temperature

With ammonia; In pyridine; methanol; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)85882-8