2,3,5-Trichloro-4-iodopyridine

Base Information

Chemical Name:2,3,5-Trichloro-4-iodopyridine
CAS No.:406676-23-1
Molecular Formula:C5H Cl3 I N
Molecular Weight:308.33
Hs Code.:2933399990
DSSTox Substance ID:DTXSID70573776
Nikkaji Number:J1.662.519A
Wikidata:Q82462596
Mol file:406676-23-1.mol

Synonyms:2,3,5-Trichloro-4-iodopyridine;406676-23-1;4-Iodo-2,3,5-trichloropyridine;MFCD11044389;SCHEMBL3896277;AMY8042;DTXSID70573776;GEO-03662;AKOS005072352;ED-0728;SY286771;CS-0332396;G14749;J-506885

Suppliers and Price of 2,3,5-Trichloro-4-iodopyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
4-Iodo-2,3,5-trichloropyridine 95%
5 g
$ 888.00

SynQuest Laboratories
4-Iodo-2,3,5-trichloropyridine 95%
1 g
$ 312.00

Matrix Scientific
2,3,5-Trichloro-4-iodopyridine >95%
1g
$ 298.00

Matrix Scientific
2,3,5-Trichloro-4-iodopyridine >95%
500mg
$ 223.00

Matrix Scientific
2,3,5-Trichloro-4-iodopyridine >95%
5g
$ 685.00

Crysdot
2,3,5-Trichloro-4-iodopyridine 95+%
1g
$ 300.00

Chemenu
2,3,5-Trichloro-4-iodopyridine 95%
5g
$ 636.00

Chemenu
2,3,5-Trichloro-4-iodopyridine 95%
1g
$ 234.00

Apolloscientific
4-Iodo-2,3,5-trichloropyridine 95%
1g
$ 283.00

Apolloscientific
4-Iodo-2,3,5-trichloropyridine 95%
5g
$ 805.00

Total 10 raw suppliers

Chemical Property of 2,3,5-Trichloro-4-iodopyridine

Chemical Property:

Vapor Pressure:0.002mmHg at 25°C
Melting Point:121-122°
Refractive Index:1.661
Boiling Point:305.018°C at 760 mmHg
PKA:-3.49±0.10(Predicted)
Flash Point:138.27°C
PSA：12.89000
Density:2.193g/cm³
LogP:3.64640
Storage Temp.:2-8°C
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:306.82193
Heavy Atom Count:10
Complexity:124

Purity/Quality:

98%min ^*data from raw suppliers

4-Iodo-2,3,5-trichloropyridine 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=C(C(=C(C(=N1)Cl)Cl)I)Cl

Technology Process of 2,3,5-Trichloro-4-iodopyridine

There total 1 articles about 2,3,5-Trichloro-4-iodopyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 16063-70-0
2,3,5-trichloropyridine

: 406676-23-1
2,3,5-trichloro-4-iodopyridine

Guidance literature:: With iodine; lithium diisopropyl amide; In tetrahydrofuran; hexane; at -75 ℃;
DOI:10.1002/1099-0690(200112)2001:23<4533::AID-EJOC4533>3.0.CO;2-1

Reference yield:

: 406676-23-1
2,3,5-trichloro-4-iodopyridine

: 2,3,5-trichloro-4,6-bis(3,5-dimethylphenyl)pyridine

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium; 2,2,6,6-tetramethyl-piperidine / tetrahydrofuran / 2 h / -100 °C / Schlenk technique; Inert atmosphere

1.2: -78 - 20 °C / Inert atmosphere

2.1: potassium phosphate; palladium diacetate; tricyclohexylphosphine / toluene; water; butan-1-ol / 19 h / 100 °C / Inert atmosphere; Sealed tube

With 2,2,6,6-tetramethyl-piperidine; potassium phosphate; n-butyllithium; palladium diacetate; tricyclohexylphosphine; In tetrahydrofuran; water; toluene; butan-1-ol; 2.1: |Suzuki-Miyaura Coupling;
DOI:10.1002/ejoc.201701718

Reference yield:

: 406676-23-1
2,3,5-trichloro-4-iodopyridine

: 4-bromo-2,3,5-trichloro-6-(3-nitrophenyl)pyridine

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium; 2,2,6,6-tetramethyl-piperidine / tetrahydrofuran / 2 h / -100 °C / Schlenk technique; Inert atmosphere

1.2: -78 - 20 °C / Inert atmosphere

2.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium phosphate / toluene; water; ethanol / 100 °C / Inert atmosphere; Sealed tube

With 2,2,6,6-tetramethyl-piperidine; potassium phosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; n-butyllithium; In tetrahydrofuran; ethanol; water; toluene; 2.1: |Suzuki-Miyaura Coupling;
DOI:10.1002/ejoc.201701718