3-(2-Methoxyethoxy)piperidine

Base Information

• Chemical Name: 3-(2-Methoxyethoxy)piperidine
• CAS No.: 946714-09-6
• Molecular Formula: C₈H₁₇NO₂
• Molecular Weight: 159.228
• European Community (EC) Number: 865-708-1
• DSSTox Substance ID: DTXSID901307371
• ChEMBL ID: CHEMBL4571864
• Mol file: 946714-09-6.mol

Synonyms:3-(2-methoxyethoxy)piperidine;946714-09-6;SCHEMBL1555763;CHEMBL4571864;DTXSID901307371;AKOS000246915;AKOS022483263;EN300-56447;A1-00676;Z334959354

Chemical Property of 3-(2-Methoxyethoxy)piperidine

Chemical Property:

• XLogP3: 0.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 159.125928785
• Heavy Atom Count: 11
• Complexity: 98.1

Purity/Quality:

97% ^*data from raw suppliers

3-(2-methoxyethoxy)piperidine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COCCOC1CCCNC1

Technology Process of 3-(2-Methoxyethoxy)piperidine

There total 1 articles about 3-(2-Methoxyethoxy)piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 3-(2-methoxyethoxy)piperidine (946714-09-6)

Guidance literature:

Reference yield: 75.0%

3-(2-methoxyethoxy)piperidine (946714-09-6) + ((1R,4R)-4-(methyl(7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-cyclohexyl)methanesulfonic acid → N-[trans-4-({[3-(2-methoxyethoxy)piperidin-1-yl]sulfonyl}methyl)cyclohexyl]-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Guidance literature:

((1R,4R)-4-(methyl(7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-cyclohexyl)methanesulfonic acid; With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; chloroform; at 20 ℃; for 1h; Inert atmosphere;

3-(2-methoxyethoxy)piperidine; With N-ethyl-N,N-diisopropylamine;

With lithium hydroxide; In tetrahydrofuran; methanol; water; at 20 ℃;