Technology Process of C17H18FN5OS
There total 6 articles about C17H18FN5OS which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2-methylpyrazin-5-carboxylic acid;
With
4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride;
In
methanol;
at 20 ℃;
for 0.0833333h;
C11H14FN3S;
In
methanol;
at 20 ℃;
for 1h;
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: hydrogen / palladium 10% on activated carbon / ethanol / 8 h / 20 °C
2.1: potassium carbonate / N,N-dimethyl-formamide / 7.5 h / 50 °C
3.1: toluene-4-sulfonic acid / toluene / 14 h / Reflux
4.1: trichlorophosphate / 23 h / 20 °C
5.1: toluene / 5.5 h / 20 - 100 °C
6.1: trifluoroacetic acid / 22 h / Reflux
7.1: 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride / methanol / 0.08 h / 20 °C
7.2: 1 h / 20 °C
With
hydrogen; potassium carbonate; toluene-4-sulfonic acid; trifluoroacetic acid; 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride; trichlorophosphate;
palladium 10% on activated carbon;
In
methanol; ethanol; N,N-dimethyl-formamide; toluene;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 7.5 h / 50 °C
2.1: toluene-4-sulfonic acid / toluene / 14 h / Reflux
3.1: trichlorophosphate / 23 h / 20 °C
4.1: toluene / 5.5 h / 20 - 100 °C
5.1: trifluoroacetic acid / 22 h / Reflux
6.1: 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride / methanol / 0.08 h / 20 °C
6.2: 1 h / 20 °C
With
potassium carbonate; toluene-4-sulfonic acid; trifluoroacetic acid; 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride; trichlorophosphate;
In
methanol; N,N-dimethyl-formamide; toluene;