(S)-5-AMinoMethyl-3-(4-Morpholinophenyl)-1,3-oxazolidin-2-one

Base Information

Chemical Name:(S)-5-AMinoMethyl-3-(4-Morpholinophenyl)-1,3-oxazolidin-2-one
CAS No.:952288-54-9
Molecular Formula:C₁₄H₁₉N₃O₃
Molecular Weight:277.323
Hs Code.:
Mol file:952288-54-9.mol

Synonyms:(S)-5-Aminomethyl-3-(4-morpholin-4-yl-phenyl)-oxazolidin-2-one

Suppliers and Price of (S)-5-AMinoMethyl-3-(4-Morpholinophenyl)-1,3-oxazolidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-5-Aminomethyl-3-(4-morpholinophenyl)-1,3-oxazolidin-2-one
250mg
$ 1190.00

TRC
(S)-5-Aminomethyl-3-(4-morpholinophenyl)-1,3-oxazolidin-2-one
25mg
$ 150.00

Medical Isotopes, Inc.
(S)-5-Aminomethyl-3-(4-morpholinophenyl)-1,3-oxazolidin-2-one
250 mg
$ 2200.00

Medical Isotopes, Inc.
(S)-5-Aminomethyl-3-(4-morpholinophenyl)-1,3-oxazolidin-2-one
25 mg
$ 650.00

Total 11 raw suppliers

Chemical Property of (S)-5-AMinoMethyl-3-(4-Morpholinophenyl)-1,3-oxazolidin-2-one

Chemical Property:

Melting Point:>110°C (subl.)
Storage Temp.:-20°C Freezer, Under inert atmosphere
Solubility.:Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

(S)-5-Aminomethyl-3-(4-morpholinophenyl)-1,3-oxazolidin-2-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses (S)-5-AMinoMethyl-3-(4-Morpholinophenyl)-1,3-oxazolidin-2-one is used in the preparation of substituted oxazolidinones, useful in the treatment of disorders associated with blood coagulation.

Technology Process of (S)-5-AMinoMethyl-3-(4-Morpholinophenyl)-1,3-oxazolidin-2-one

There total 4 articles about (S)-5-AMinoMethyl-3-(4-Morpholinophenyl)-1,3-oxazolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 264601-17-4
(R)-3-(4'-N-morpholinophenyl)-5-(hydroxymethyl)-oxazolidin-2-one

: 952288-54-9
(S)-5-Aminomethyl-3-(4-morpholin-4-yl-phenyl)-oxazolidin-2-one

Guidance literature:: (R)-3-(4'-N-morpholinophenyl)-5-(hydroxymethyl)-oxazolidin-2-one; With methanesulfonyl chloride; triethylamine; In dichloromethane; at 0 - 20 ℃;

With potassium phtalimide; In acetonitrile; at 180 ℃; for 0.75h; microwave irradiation;

With hydrazine hydrate; In methanol; for 2h; Heating;
DOI:10.1021/jm050101d

Reference yield:

: 939963-89-0
(R)-3-(4'-N-morpholinophenyl)-5-(azidomethyl)-oxazolidin-2-one

: 952288-54-9
(S)-5-Aminomethyl-3-(4-morpholin-4-yl-phenyl)-oxazolidin-2-one

Guidance literature:: With palladium on activated charcoal; hydrogen; In ethyl acetate; at 20 ℃;
DOI:10.1039/b812372a

Reference yield:

: 348626-43-7
4-(4-morpholinyl)-N-benzyloxycarbonylaniline

: 952288-54-9
(S)-5-Aminomethyl-3-(4-morpholin-4-yl-phenyl)-oxazolidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-BuLi; isoamyl alcohol / tetrahydrofuran; hexane / 0.17 h / -78 °C

1.2: tetrahydrofuran; hexane / -78 - 20 °C

2.1: MeSO₂Cl; Et₃N / CH₂Cl₂ / 0 - 20 °C

2.2: potassium phthalimide / acetonitrile / 0.75 h / 180 °C / microwave irradiation

2.3: hydrazine hydrate / methanol / 2 h / Heating

With n-butyllithium; i-Amyl alcohol; methanesulfonyl chloride; triethylamine; In tetrahydrofuran; hexane; dichloromethane;
DOI:10.1021/jm050101d