3-(2-Bromo-4-fluorophenyl)propan-1-ol

Base Information

Chemical Name:3-(2-Bromo-4-fluorophenyl)propan-1-ol
CAS No.:404575-32-2
Molecular Formula:C9H10 Br F O
Molecular Weight:233.08
Hs Code.:
DSSTox Substance ID:DTXSID60476464
Mol file:404575-32-2.mol

Synonyms:404575-32-2;3-(2-Bromo-4-fluorophenyl)propan-1-ol;3-(2-BROMO-4-FLUORO-PHENYL)-PROPAN-1-OL;SCHEMBL3637969;DTXSID60476464;AKOS011897666;EN300-1624525

Suppliers and Price of 3-(2-Bromo-4-fluorophenyl)propan-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3-(2-BROMO-4-FLUORO-PHENYL)-PROPAN-1-OL 95.00%
5MG
$ 503.07

Total 4 raw suppliers

Chemical Property of 3-(2-Bromo-4-fluorophenyl)propan-1-ol

Chemical Property:

Vapor Pressure:0.001mmHg at 25°C
Refractive Index:1.547
Boiling Point:295.772°C at 760 mmHg
Flash Point:132.678°C
PSA：20.23000
Density:1.488g/cm³
LogP:2.51310
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:231.98991
Heavy Atom Count:12
Complexity:132

Purity/Quality:

97% ^*data from raw suppliers

3-(2-BROMO-4-FLUORO-PHENYL)-PROPAN-1-OL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1F)Br)CCCO

Technology Process of 3-(2-Bromo-4-fluorophenyl)propan-1-ol

There total 4 articles about 3-(2-Bromo-4-fluorophenyl)propan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: methyl 3-(2-bromo-4-fluorophenyl)propanoate

: 404575-32-2
3-(2-Bromo-4-fluorophenyl)propan-1-ol

Guidance literature:: methyl 3-(2-bromo-4-fluorophenyl)propanoate; With diisobutylaluminium hydride; In toluene; at -50 - 0 ℃; for 1.83333h;

With hydrogenchloride; water; In toluene; at 40 ℃;

Reference yield:

: 59142-68-6
2-bromo-4-fluorobenzaldehyde

: 404575-32-2
3-(2-Bromo-4-fluorophenyl)propan-1-ol

Guidance literature:: Multi-step reaction with 2 steps

1: formic acid; triethylamine / 4 h / 0 - 95 °C

2: lithium aluminium tetrahydride / diethyl ether / 3.5 h / Reflux

With lithium aluminium tetrahydride; formic acid; triethylamine; In diethyl ether;
DOI:10.1021/acs.orglett.9b03498