(R/S)-1-<3-(5-hydroxy-1,2,3,4-tetrahydro-1-naphtalenyl)propyl>-4-phenylpiperazine

Base Information

• Chemical Name: (R/S)-1-<3-(5-hydroxy-1,2,3,4-tetrahydro-1-naphtalenyl)propyl>-4-phenylpiperazine
• CAS No.: 214957-39-8
• Molecular Formula: C₂₃H₃₀N₂O
• Molecular Weight: 350.504

Synonyms:(R/S)-1-<3-(5-hydroxy-1,2,3,4-tetrahydro-1-naphtalenyl)propyl>-4-phenylpiperazine

Chemical Property of (R/S)-1-<3-(5-hydroxy-1,2,3,4-tetrahydro-1-naphtalenyl)propyl>-4-phenylpiperazine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

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Technology Process of (R/S)-1-<3-(5-hydroxy-1,2,3,4-tetrahydro-1-naphtalenyl)propyl>-4-phenylpiperazine

There total 1 articles about (R/S)-1-<3-(5-hydroxy-1,2,3,4-tetrahydro-1-naphtalenyl)propyl>-4-phenylpiperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

(R/S)-1-<3-(5-methoxy-1,2,3,4-tetrahydro-1-naphtalenyl)propyl>-4-phenylpiperazine → (R/S)-1-<3-(5-hydroxy-1,2,3,4-tetrahydro-1-naphtalenyl)propyl>-4-phenylpiperazine (214957-39-8)

Guidance literature:

With boron tribromide; In dichloromethane; Ambient temperature;

DOI:10.1006/bioo.1998.1089

Reference yield:

[11C]methyl iodide (54245-42-0) + (R/S)-1-<3-(5-hydroxy-1,2,3,4-tetrahydro-1-naphtalenyl)propyl>-4-phenylpiperazine (214957-39-8) → (R/S)--1-<3-(5-methoxy-1,2,3,4-tetrahydro-1-naphtalenyl)propyl>-4-phenylpiperazine

Guidance literature:

With potassium tert-butylate; In N,N-dimethyl-formamide;

DOI:10.1006/bioo.1998.1089

Reference yield:

[11C]methyl iodide (54245-42-0) + (R/S)-1-<3-(5-hydroxy-1,2,3,4-tetrahydro-1-naphtalenyl)propyl>-4-phenylpiperazine (214957-39-8) → [11C]methanol (13036-26-5) + (R/S)--1-<3-(5-methoxy-1,2,3,4-tetrahydro-1-naphtalenyl)propyl>-4-phenylpiperazine

Guidance literature:

With potassium tert-butylate; In N,N-dimethyl-formamide; for 0.025h; Product distribution; Ambient temperature; var. base; var temp.;

DOI:10.1006/bioo.1998.1089

Downstream raw materials:

[11C]methanol

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