N-(4-fluorophenyl)-2-{[4-(tricyclo[3.3.1.1^3,7]dec-1-yl)quinolin-2-yl]carbonyl}hydrazinecarboxamide

Base Information

• Chemical Name: N-(4-fluorophenyl)-2-{[4-(tricyclo[3.3.1.1^3,7]dec-1-yl)quinolin-2-yl]carbonyl}hydrazinecarboxamide
• CAS No.: 1621608-40-9
• Molecular Formula: C₂₇H₂₇FN₄O₂
• Molecular Weight: 458.535

Synonyms:N-(4-fluorophenyl)-2-{[4-(tricyclo[3.3.1.1^3,7]dec-1-yl)quinolin-2-yl]carbonyl}hydrazinecarboxamide

Chemical Property of N-(4-fluorophenyl)-2-{[4-(tricyclo[3.3.1.1^3,7]dec-1-yl)quinolin-2-yl]carbonyl}hydrazinecarboxamide

Chemical Property:

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Technology Process of N-(4-fluorophenyl)-2-{[4-(tricyclo[3.3.1.1^3,7]dec-1-yl)quinolin-2-yl]carbonyl}hydrazinecarboxamide

There total 1 articles about N-(4-fluorophenyl)-2-{[4-(tricyclo[3.3.1.1^3,7]dec-1-yl)quinolin-2-yl]carbonyl}hydrazinecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

4-(adamantan-1-yl)-2-quinolinecarbohydrazide (824935-09-3) + para-fluorophenyl isocyanate (1195-45-5) → N-(4-fluorophenyl)-2-{[4-(tricyclo[3.3.1.13,7]dec-1-yl)quinolin-2-yl]carbonyl}hydrazinecarboxamide (1621608-40-9)

Guidance literature:

In tetrahydrofuran; at 20 ℃; for 4h;

DOI:10.1016/j.ejmech.2014.07.100

upstream raw materials:

4-(adamantan-1-yl)-2-quinolinecarbohydrazide

para-fluorophenyl isocyanate

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