4-chloro-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid

Base Information

Chemical Name:4-chloro-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid
CAS No.:1086423-46-2
Molecular Formula:C₁₇H₂₅ClN₂O₂Si
Molecular Weight:352.936
Hs Code.:
Mol file:1086423-46-2.mol

Synonyms:4-chloro-1-triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid

Suppliers and Price of 4-chloro-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Crysdot
4-Chloro-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine-5-carboxylicacid 97%
1g
$ 474.00

Chemenu
4-Chloro-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine-5-carboxylicacid 97%
1g
$ 448.00

Total 1 raw suppliers

Chemical Property of 4-chloro-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid

Chemical Property:

Purity/Quality:: 4-Chloro-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine-5-carboxylicacid 97% ^*data from reagent suppliers

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Pictogram(s):
Hazard Codes:

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Technology Process of 4-chloro-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid

There total 1 articles about 4-chloro-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 55052-28-3
4-chloro-7-azaindole

: 1086423-46-2
4-chloro-1-triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C

1.2: -78 - 20 °C

2.1: sec.-butyllithium / tetrahydrofuran / 0.75 h / -78 °C

2.2: 2 h

2.3: pH 2

With n-butyllithium; sec.-butyllithium; In tetrahydrofuran; hexane;

Reference yield:

: 1086423-46-2
4-chloro-1-triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid

: 1086423-49-5
{3-[(4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carbonyl)-amino]-4-methyl-phenyl}-carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 1 h / 0 - 20 °C

2: N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C

3: sodium hydroxide; water / methanol / 4 h / 20 °C

With sodium hydroxide; oxalyl dichloride; water; N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide; In methanol; dichloromethane;

Reference yield:

: 1086423-46-2
4-chloro-1-triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid

: C₂₁H₂₅N₅O₃

Guidance literature:: Multi-step reaction with 4 steps

1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 1 h / 0 - 20 °C

2: N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C

3: sodium hydroxide; water / methanol / 4 h / 20 °C

4: ethyl methyl ether; water / 0.5 h / 130 °C / microwave irradiation

With sodium hydroxide; oxalyl dichloride; water; N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide; In methanol; ethyl methyl ether; dichloromethane; water;