(2-oxo-2,3-dihydro-5-furylmethyl)triphenylphosphonium bromide

Base Information

• Chemical Name: (2-oxo-2,3-dihydro-5-furylmethyl)triphenylphosphonium bromide
• CAS No.: 78508-89-1
• Molecular Formula: Br*C₂₃H₂₀O₂P
• Molecular Weight: 439.288
• Mol file: 78508-89-1.mol

Synonyms:(2-oxo-2,3-dihydro-5-furylmethyl)triphenylphosphonium bromide

Chemical Property of (2-oxo-2,3-dihydro-5-furylmethyl)triphenylphosphonium bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2-oxo-2,3-dihydro-5-furylmethyl)triphenylphosphonium bromide

There total 6 articles about (2-oxo-2,3-dihydro-5-furylmethyl)triphenylphosphonium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

γ-bromomethyl-α,β-butenolide (78508-87-9) + triphenylphosphine (603-35-0) → (2-oxo-2,3-dihydro-5-furylmethyl)triphenylphosphonium bromide (78508-89-1)

Guidance literature:

In benzene; Ambient temperature;

DOI:10.1016/S0040-4039(01)90352-1

Reference yield:

methyl (2E)-penta-2,4-dienoate (2409-87-2) → (2-oxo-2,3-dihydro-5-furylmethyl)triphenylphosphonium bromide (78508-89-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 13 percent / NBS / H₂O / 4 h / Ambient temperature

2: 41 percent / conc. methanolic HCl / 2.25 h / Irradiation

3: 63 percent / benzene / 1.) 22 h, 2.) room tempeature, 48 h

With hydrogenchloride; N-Bromosuccinimide; In water; benzene;

DOI:10.1016/0040-4020(82)87016-6

Reference yield:

(E)-5-bromo-4-hydroxy-2-pentenoic acid (78508-86-8) → (2-oxo-2,3-dihydro-5-furylmethyl)triphenylphosphonium bromide (78508-89-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 74.4 percent / conc. HCl / H₂O / 2 h / Irradiation

2: 63 percent / benzene / 1.) 22 h, 2.) room tempeature, 48 h

With hydrogenchloride; In water; benzene;

DOI:10.1016/0040-4020(82)87016-6

upstream raw materials:

γ-bromomethyl-α,β-butenolide

triphenylphosphine

(E)-5-bromo-4-hydroxy-2-pentenoic acid

methyl (Z)-2,4-pentadienoate

Downstream raw materials:

4-hydroxycarbonyl-2-oxobutyltriphenylphosphonium bromide

(E)-6-(4-nitrophenyl)-4-oxo-5-hexenoic acid

methyl (E)-6-(4-nitrophenyl)-4-oxo-5-hexenoate

Triphenylphosphine oxide