Chloro-acetic acid (R)-cyclohexyl-(diisopropoxy-phosphoryl)-methyl ester

Base Information

Chemical Name:Chloro-acetic acid (R)-cyclohexyl-(diisopropoxy-phosphoryl)-methyl ester
CAS No.:208180-76-1
Molecular Formula:C₁₅H₂₈ClO₅P
Molecular Weight:354.811
Hs Code.:

Synonyms:Chloro-acetic acid (R)-cyclohexyl-(diisopropoxy-phosphoryl)-methyl ester

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Chemical Property of Chloro-acetic acid (R)-cyclohexyl-(diisopropoxy-phosphoryl)-methyl ester

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Technology Process of Chloro-acetic acid (R)-cyclohexyl-(diisopropoxy-phosphoryl)-methyl ester

There total 2 articles about Chloro-acetic acid (R)-cyclohexyl-(diisopropoxy-phosphoryl)-methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

: Chloro-acetic acid cyclohexyl-(diisopropoxy-phosphoryl)-methyl ester

: 208180-65-8
((S)-Cyclohexyl-hydroxy-methyl)-phosphonic acid diisopropyl ester

: 208180-85-2
((R)-Cyclohexyl-hydroxy-methyl)-phosphonic acid diisopropyl ester

: 208180-76-1
Chloro-acetic acid (R)-cyclohexyl-(diisopropoxy-phosphoryl)-methyl ester

Guidance literature:: With tert-butyl methyl ether; phosphate buffer pH 7.0; In hexane; for 100.5h; Yields of byproduct given; lipase AP 6 (Aspergillus niger);
DOI:10.1007/PL00000099

Reference yield:

: Chloro-acetic acid cyclohexyl-(diisopropoxy-phosphoryl)-methyl ester

: 208180-65-8
((S)-Cyclohexyl-hydroxy-methyl)-phosphonic acid diisopropyl ester

: 208180-85-2
((R)-Cyclohexyl-hydroxy-methyl)-phosphonic acid diisopropyl ester

: Chloro-acetic acid (S)-cyclohexyl-(diisopropoxy-phosphoryl)-methyl ester

: 208180-76-1
Chloro-acetic acid (R)-cyclohexyl-(diisopropoxy-phosphoryl)-methyl ester

Guidance literature:: With tert-butyl methyl ether; phosphate buffer pH 7.0; In hexane; for 6.5h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; lipase AP 6 (Aspergillus niger);
DOI:10.1007/PL00000099