hexa-O-acetyl-6'-azido-4'-O-benzoyl-pentakis(N-tert-butoxycarbonyl)-6'-deoxyparomomycin

Base Information

• Chemical Name: hexa-O-acetyl-6'-azido-4'-O-benzoyl-pentakis(N-tert-butoxycarbonyl)-6'-deoxyparomomycin
• CAS No.: 1234786-54-9
• Molecular Formula: C₆₇H₁₀₀N₈O₃₀
• Molecular Weight: 1497.57
• Mol file: 1234786-54-9.mol

Synonyms:hexa-O-acetyl-6'-azido-4'-O-benzoyl-pentakis(N-tert-butoxycarbonyl)-6'-deoxyparomomycin

Chemical Property of hexa-O-acetyl-6'-azido-4'-O-benzoyl-pentakis(N-tert-butoxycarbonyl)-6'-deoxyparomomycin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of hexa-O-acetyl-6'-azido-4'-O-benzoyl-pentakis(N-tert-butoxycarbonyl)-6'-deoxyparomomycin

There total 1 articles about hexa-O-acetyl-6'-azido-4'-O-benzoyl-pentakis(N-tert-butoxycarbonyl)-6'-deoxyparomomycin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

hexa-O-acetyl-6'-bromo-4'-O-benzoyl-pentakis(N-tert-butoxycarbonyl)-6'-deoxyparomomycin (875125-22-7) → hexa-O-acetyl-6'-azido-4'-O-benzoyl-pentakis(N-tert-butoxycarbonyl)-6'-deoxyparomomycin (1234786-54-9)

Guidance literature:

With sodium azide; In N,N-dimethyl-formamide; at 80 ℃; for 4h;

DOI:10.1002/ejoc.201000182

Reference yield: 80.0%

hexa-O-acetyl-6'-azido-4'-O-benzoyl-pentakis(N-tert-butoxycarbonyl)-6'-deoxyparomomycin (1234786-54-9) → 6'-azido-6'-deoxyparomomycin penta(trifluoroacetate)

Guidance literature:

hexa-O-acetyl-6'-azido-4'-O-benzoyl-pentakis(N-tert-butoxycarbonyl)-6'-deoxyparomomycin; With ammonia; In methanol; at 60 ℃; for 9h;

With water; trifluoroacetic acid; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1002/ejoc.201000182

upstream raw materials:

hexa-O-acetyl-6'-bromo-4'-O-benzoyl-pentakis(N-tert-butoxycarbonyl)-6'-deoxyparomomycin