(2'S,3'S,4'R)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(4'-O-hexacosanoyl-D-ribo-tetradecyl)-ethane

Base Information

• Chemical Name: (2'S,3'S,4'R)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(4'-O-hexacosanoyl-D-ribo-tetradecyl)-ethane
• CAS No.: 1301629-47-9
• Molecular Formula: C₇₉H₁₂₄O₉
• Molecular Weight: 1217.85
• Mol file: 1301629-47-9.mol

Synonyms:(2'S,3'S,4'R)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(4'-O-hexacosanoyl-D-ribo-tetradecyl)-ethane

Chemical Property of (2'S,3'S,4'R)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(4'-O-hexacosanoyl-D-ribo-tetradecyl)-ethane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2'S,3'S,4'R)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(4'-O-hexacosanoyl-D-ribo-tetradecyl)-ethane

There total 11 articles about (2'S,3'S,4'R)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(4'-O-hexacosanoyl-D-ribo-tetradecyl)-ethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2'S,3'R,4'R)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(3',4'-O-isopropylidene-2'-O-hexacosanoyl-D-ribo-heptadecyl)-ethane (1301629-45-7) → (2'S,3'S,4'R)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(2'-O-hexacosanoyl-D-ribo-tetradecyl)-ethane (1301629-46-8) + (2'S,3'S,4'R)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(4'-O-hexacosanoyl-D-ribo-tetradecyl)-ethane (1301629-47-9)

Guidance literature:

With hydrogenchloride; In methanol; water; at 20 ℃;

DOI:10.1016/j.bmcl.2011.02.044

Reference yield:

(2'S,3'S,4'R)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(3',4';-O-isopropylidene-2'-O-(para-methoxybenzyl)-D-ribo-heptadecyl)-ethane (1221720-08-6) → (2'S,3'S,4'R)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(2'-O-hexacosanoyl-D-ribo-tetradecyl)-ethane (1301629-46-8) + (2'S,3'S,4'R)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(4'-O-hexacosanoyl-D-ribo-tetradecyl)-ethane (1301629-47-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane; water / 0.67 h / 20 °C

2: dmap; 1-hexacosanoic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 18 h / 26 - 28 °C

3: hydrogenchloride / methanol; water / 20 °C

With hydrogenchloride; dmap; 1-hexacosanoic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In methanol; dichloromethane; water;

DOI:10.1016/j.bmcl.2011.02.044

Reference yield:

(2'S,3'S,4'R)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(3',4';-O-isopropylidene-D-ribo-heptadecyl)-ethane (1221720-10-0) → (2'S,3'S,4'R)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(2'-O-hexacosanoyl-D-ribo-tetradecyl)-ethane (1301629-46-8) + (2'S,3'S,4'R)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(4'-O-hexacosanoyl-D-ribo-tetradecyl)-ethane (1301629-47-9)

Guidance literature:

Multi-step reaction with 2 steps

1: dmap; 1-hexacosanoic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 18 h / 26 - 28 °C

2: hydrogenchloride / methanol; water / 20 °C

With hydrogenchloride; dmap; 1-hexacosanoic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In methanol; dichloromethane; water;

DOI:10.1016/j.bmcl.2011.02.044

upstream raw materials:

(2'S,3'S,4'R)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(3',4'-O-isopropylidene-2'-O-(para-methoxybenzyl)-D-ribo-heptadec-5',6'-enyl)-acetylene

(2'S,3'S,4'R)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(3',4';-O-isopropylidene-2'-O-(para-methoxybenzyl)-D-ribo-heptadecyl)-ethane

(2'S,3'S,4'R)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(3',4';-O-isopropylidene-D-ribo-heptadecyl)-ethane

(2'S,3'R,4'R)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(3',4'-O-isopropylidene-2'-O-hexacosanoyl-D-ribo-heptadecyl)-ethane