Technology Process of C28H23N7O
There total 12 articles about C28H23N7O which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
palladium diacetate; sodium carbonate; XPhos;
In
1-methyl-pyrrolidin-2-one;
at 160 ℃;
for 1.5h;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: N,N-dimethyl-formamide; oxalyl dichloride / dichloromethane / 2.08 h / 20 °C
1.2: 2 h / 20 °C
2.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -30 - -10 °C / Inert atmosphere
2.2: 2 h / -50 - -10 °C / Inert atmosphere
3.1: triethylamine / butan-1-ol / Reflux
4.1: palladium diacetate; XPhos; sodium carbonate / 1-methyl-pyrrolidin-2-one / 1.5 h / 160 °C / Inert atmosphere
With
n-butyllithium; oxalyl dichloride; palladium diacetate; sodium carbonate; triethylamine; N,N-dimethyl-formamide; XPhos;
In
tetrahydrofuran; 1-methyl-pyrrolidin-2-one; hexane; dichloromethane; butan-1-ol;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: hydrogenchloride / water; isopropyl alcohol / 3 h / 65 °C
2: triethylamine / butan-1-ol / Reflux
3: palladium diacetate; XPhos; sodium carbonate / 1-methyl-pyrrolidin-2-one / 1.5 h / 160 °C / Inert atmosphere
With
hydrogenchloride; palladium diacetate; sodium carbonate; triethylamine; XPhos;
In
1-methyl-pyrrolidin-2-one; water; isopropyl alcohol; butan-1-ol;
