Pyrazinecarboxamide, 6-fluoro- (9CI)

Base Information

• Chemical Name: Pyrazinecarboxamide, 6-fluoro- (9CI)
• CAS No.: 356783-47-6
• Molecular Formula: C₅H₄FN₃O
• Molecular Weight: 141.105
• Hs Code.: 2934999090
• Mol file: 356783-47-6.mol

Synonyms:Pyrazinecarboxamide,6-fluoro- (9CI); 6-Fluoro-2-pyrazinecarboxamide

Chemical Property of Pyrazinecarboxamide, 6-fluoro- (9CI)

Chemical Property:

• PSA: 68.87000
• LogP: 0.41490

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Des-(3,4-Dihydrogen-3-oxo) Favipiravir is a building block related to Favipiravir(F103350). Favipiravir is used for the treatment of advanced Ebola virus infection in a small animal model. Favipiravir suppressed the replication of Zaire Ebola virus and prevented a lethal outcome in 100% of the animals. Based on the studies, Favipiravir can be a candidate for the treatment of Ebola hemorrhagic fever.

Technology Process of Pyrazinecarboxamide, 6-fluoro- (9CI)

There total 1 articles about Pyrazinecarboxamide, 6-fluoro- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-fluoro-2-pyrazinecarbonitrile (356783-46-5) → 6-fluoro-2-pyrazinecarboxamide (356783-47-6)

Guidance literature:

With sodium chloride; In hydrogenchloride; water; ethyl acetate;

upstream raw materials:

6-fluoro-2-pyrazinecarbonitrile