ethyl (Z)-2-benzyl-3-[(2S,3R)-1-methoxy-3-methylpentan-2-ylamino]but-2-enoate

Base Information

• Chemical Name: ethyl (Z)-2-benzyl-3-[(2S,3R)-1-methoxy-3-methylpentan-2-ylamino]but-2-enoate
• CAS No.: 1018827-86-5
• Molecular Formula: C₂₀H₃₁NO₃
• Molecular Weight: 333.471
• Mol file: 1018827-86-5.mol

Synonyms:ethyl (Z)-2-benzyl-3-[(2S,3R)-1-methoxy-3-methylpentan-2-ylamino]but-2-enoate

Chemical Property of ethyl (Z)-2-benzyl-3-[(2S,3R)-1-methoxy-3-methylpentan-2-ylamino]but-2-enoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl (Z)-2-benzyl-3-[(2S,3R)-1-methoxy-3-methylpentan-2-ylamino]but-2-enoate

There total 1 articles about ethyl (Z)-2-benzyl-3-[(2S,3R)-1-methoxy-3-methylpentan-2-ylamino]but-2-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C7H17NO (1018827-77-4) + Ethyl 2-benzylacetoacetate (620-79-1) → ethyl (Z)-2-benzyl-3-[(2S,3R)-1-methoxy-3-methylpentan-2-ylamino]but-2-enoate (1018827-86-5)

Guidance literature:

With 4 A molecular sieve; In hexane; at 50 ℃;

DOI:10.1021/ja710408f

Reference yield:

ethyl (Z)-2-benzyl-3-[(2S,3R)-1-methoxy-3-methylpentan-2-ylamino]but-2-enoate (1018827-86-5) + phenylacetylene (536-74-3) → ethyl (S)-2-benzyl-2-ethanoyl-3-phenylbut-3-enoate + ethyl (R)-2-benzyl-2-ethanoyl-3-phenylbut-3-enoate (1018828-03-9)

Guidance literature:

ethyl (Z)-2-benzyl-3-[(2S,3R)-1-methoxy-3-methylpentan-2-ylamino]but-2-enoate; phenylacetylene; With indium(III) triflate; n-butyllithium; In hexane; at 120 ℃; for 18h;

With acetic acid; In tetrahydrofuran; hexane; Further stages. Title compound not separated from byproducts.;

DOI:10.1021/ja710408f

upstream raw materials:

C₇H₁₇NO

Ethyl 2-benzylacetoacetate

Downstream raw materials:

ethyl (R)-2-benzyl-2-ethanoyl-3-phenylbut-3-enoate