(3-acetoxy-2-O-benzoyl-1-propoxy)methyl azide

Base Information

• Chemical Name: (3-acetoxy-2-O-benzoyl-1-propoxy)methyl azide
• CAS No.: 476372-29-9
• Molecular Formula: C₁₃H₁₅N₃O₅
• Molecular Weight: 293.279
• Mol file: 476372-29-9.mol

Synonyms:(3-acetoxy-2-O-benzoyl-1-propoxy)methyl azide

Chemical Property of (3-acetoxy-2-O-benzoyl-1-propoxy)methyl azide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of (3-acetoxy-2-O-benzoyl-1-propoxy)methyl azide

There total 2 articles about (3-acetoxy-2-O-benzoyl-1-propoxy)methyl azide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

(3-acetoxy-2-O-benzoyl-1-propoxy)methyl bromide (380897-71-2) → (3-acetoxy-2-O-benzoyl-1-propoxy)methyl azide (476372-29-9)

Guidance literature:

With sodium azide; In N,N-dimethyl-formamide; at 90 ℃; for 4h;

DOI:10.1016/S0014-827X(01)01152-1

Reference yield:

1,3-dioxan-5-ol benzoate (49784-60-3) → (3-acetoxy-2-O-benzoyl-1-propoxy)methyl azide (476372-29-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 93 percent / NaN₃ / dimethylformamide / 4 h / 90 °C

With sodium azide; In N,N-dimethyl-formamide;

DOI:10.1016/S0014-827X(01)01152-1

Reference yield: 64.0%

4-benzylsulfanyl-1-prop-2-ynyl-1H-pyrazolo[3,4-d]pyrimidine (328390-35-8) + (3-acetoxy-2-O-benzoyl-1-propoxy)methyl azide (476372-29-9) → 1-[1-(3-acetoxy-2-O-benzoyl-1-propoxy)methyl-1,2,3-triazol-4-ylmethyl]-4-benzylthio-1H-pyrazolo[3,4-d]pyrimidine + 1-[1-(3-acetoxy-2-O-benzoyl-1-propoxy)methyl-1,2,3-triazol-5-ylmethyl]-4-benzylthio-1H-pyrazolo[3,4-d]pyrimidine

Guidance literature:

In toluene; for 38h; Heating;

DOI:10.1016/S0014-827X(01)01152-1

upstream raw materials:

(3-acetoxy-2-O-benzoyl-1-propoxy)methyl bromide

1,3-dioxan-5-ol benzoate

Refernces