2-N-{2-[bis(2-{10β-dihydroartemisinoxy}ethyl)amino]ethyl}-6-(morpholin-4-yl)-4-N-phenyl-1,3,5-triazine-2,4-diamine

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Chemical Name:2-N-{2-[bis(2-{10β-dihydroartemisinoxy}ethyl)amino]ethyl}-6-(morpholin-4-yl)-4-N-phenyl-1,3,5-triazine-2,4-diamine
CAS No.:1584056-14-3
Molecular Formula:C₄₉H₇₃N₇O₁₁
Molecular Weight:936.159
Hs Code.:

Synonyms:2-N-{2-[bis(2-{10β-dihydroartemisinoxy}ethyl)amino]ethyl}-6-(morpholin-4-yl)-4-N-phenyl-1,3,5-triazine-2,4-diamine

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Chemical Property of 2-N-{2-[bis(2-{10β-dihydroartemisinoxy}ethyl)amino]ethyl}-6-(morpholin-4-yl)-4-N-phenyl-1,3,5-triazine-2,4-diamine

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Technology Process of 2-N-{2-[bis(2-{10β-dihydroartemisinoxy}ethyl)amino]ethyl}-6-(morpholin-4-yl)-4-N-phenyl-1,3,5-triazine-2,4-diamine

There total 4 articles about 2-N-{2-[bis(2-{10β-dihydroartemisinoxy}ethyl)amino]ethyl}-6-(morpholin-4-yl)-4-N-phenyl-1,3,5-triazine-2,4-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 139191-20-1
2-N-(2-aminoethyl)-6-(morpholin-4-yl)-4-N-phenyl-1,3,5-triazine-2,4-diamine

: 101834-30-4
2-(10β-dihydroartemisinoxy)propyl bromide

: 1584056-14-3
2-N-{2-[bis(2-{10β-dihydroartemisinoxy}ethyl)amino]ethyl}-6-(morpholin-4-yl)-4-N-phenyl-1,3,5-triazine-2,4-diamine

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 50 ℃; for 0.0666667h; Microwave irradiation;
DOI:10.1016/j.ejmech.2014.01.040

Reference yield:

: 2272-40-4
2-phenylamino-4,6-dichloro-s-triazine

: 1584056-14-3
2-N-{2-[bis(2-{10β-dihydroartemisinoxy}ethyl)amino]ethyl}-6-(morpholin-4-yl)-4-N-phenyl-1,3,5-triazine-2,4-diamine

Guidance literature:: Multi-step reaction with 3 steps

1: sodium carbonate / acetone / 0 - 20 °C

2: 50 - 70 °C

3: potassium carbonate / N,N-dimethyl-formamide / 0.07 h / 50 °C / Microwave irradiation

With sodium carbonate; potassium carbonate; In N,N-dimethyl-formamide; acetone;
DOI:10.1016/j.ejmech.2014.01.040

Reference yield:

: 62-53-3
aniline

: 1584056-14-3
2-N-{2-[bis(2-{10β-dihydroartemisinoxy}ethyl)amino]ethyl}-6-(morpholin-4-yl)-4-N-phenyl-1,3,5-triazine-2,4-diamine

Guidance literature:: Multi-step reaction with 4 steps

1: sodium carbonate / acetone / 6 h / 0 °C

2: sodium carbonate / acetone / 0 - 20 °C

3: 50 - 70 °C

4: potassium carbonate / N,N-dimethyl-formamide / 0.07 h / 50 °C / Microwave irradiation

With sodium carbonate; potassium carbonate; In N,N-dimethyl-formamide; acetone;
DOI:10.1016/j.ejmech.2014.01.040