3-(S)-(1-(R)-(1,3-diethyl-4,5-dihydrospiro[cyclopentapyrazole-6(1H),4'-piperidin-1'-yl])eth-1-yl)-4-(S)-(3-fluorophenyl)cyclopentan-1-one

Base Information

Chemical Name:3-(S)-(1-(R)-(1,3-diethyl-4,5-dihydrospiro[cyclopentapyrazole-6(1H),4'-piperidin-1'-yl])eth-1-yl)-4-(S)-(3-fluorophenyl)cyclopentan-1-one
CAS No.:849204-08-6
Molecular Formula:C₂₇H₃₆FN₃O
Molecular Weight:437.601
Hs Code.:

Synonyms:3-(S)-(1-(R)-(1,3-diethyl-4,5-dihydrospiro[cyclopentapyrazole-6(1H),4'-piperidin-1'-yl])eth-1-yl)-4-(S)-(3-fluorophenyl)cyclopentan-1-one

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Chemical Property of 3-(S)-(1-(R)-(1,3-diethyl-4,5-dihydrospiro[cyclopentapyrazole-6(1H),4'-piperidin-1'-yl])eth-1-yl)-4-(S)-(3-fluorophenyl)cyclopentan-1-one

Chemical Property:

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Technology Process of 3-(S)-(1-(R)-(1,3-diethyl-4,5-dihydrospiro[cyclopentapyrazole-6(1H),4'-piperidin-1'-yl])eth-1-yl)-4-(S)-(3-fluorophenyl)cyclopentan-1-one

There total 2 articles about 3-(S)-(1-(R)-(1,3-diethyl-4,5-dihydrospiro[cyclopentapyrazole-6(1H),4'-piperidin-1'-yl])eth-1-yl)-4-(S)-(3-fluorophenyl)cyclopentan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 849204-07-5
1-(S)-(1-(R)-(1,3-diethyl-4,5-dihydrospiro[cyclopentapyrazole-6(1H),4'-piperidin-1'-yl])eth-1-yl)-4-methylene-2-(S)-(3-fluorophenyl)cyclopentane

: 849204-08-6
3-(S)-(1-(R)-(1,3-diethyl-4,5-dihydrospiro[cyclopentapyrazole-6(1H),4'-piperidin-1'-yl])eth-1-yl)-4-(S)-(3-fluorophenyl)cyclopentan-1-one

Guidance literature:: With hydrogenchloride; dimethylsulfide; ozone; In methanol; diethyl ether; at -70 - 20 ℃; for 1h; Product distribution / selectivity;

Reference yield:

: 849204-09-7
C₂₈H₄₀FN₃O₂

: 849204-08-6
3-(S)-(1-(R)-(1,3-diethyl-4,5-dihydrospiro[cyclopentapyrazole-6(1H),4'-piperidin-1'-yl])eth-1-yl)-4-(S)-(3-fluorophenyl)cyclopentan-1-one

Guidance literature:: With sodium periodate; In tetrahydrofuran; water; at 20 ℃; for 2h; Product distribution / selectivity;

Reference yield:

: 849204-08-6
3-(S)-(1-(R)-(1,3-diethyl-4,5-dihydrospiro[cyclopentapyrazole-6(1H),4'-piperidin-1'-yl])eth-1-yl)-4-(S)-(3-fluorophenyl)cyclopentan-1-one

: 13518-40-6,75898-43-0,104944-18-5
t-butyl D-valinate hydrochloride

: 849204-10-0
C₃₆H₅₅FN₄O₂

Guidance literature:: 3-(S)-(1-(R)-(1,3-diethyl-4,5-dihydrospiro[cyclopentapyrazole-6(1H),4'-piperidin-1'-yl])eth-1-yl)-4-(S)-(3-fluorophenyl)cyclopentan-1-one; t-butyl D-valinate hydrochloride; With N-ethyl-N,N-diisopropylamine; In 1,2-dichloro-ethane; for 0.25h;

With sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane; at 20 - 50 ℃; for 19h;