PGF2alpha-EA

Base Information

Chemical Name:PGF2alpha-EA
CAS No.:353787-70-9
Molecular Formula:C₂₂H₃₉NO₅
Molecular Weight:397.555
Hs Code.:
Nikkaji Number:J2.039.319J
Wikidata:Q27123950
Metabolomics Workbench ID:2436
Mol file:353787-70-9.mol

Synonyms:Dinoprost ethanolamide;PGF2alpha-EA;353787-70-9;PMF2alpha;Prostamide-F2alpha;Prostaglandin F2alpha-EA;prostaglandin F2alpha 1-ethanolamide;(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]-N-(2-hydroxyethyl)hept-5-enamide;Prostaglandin F2alpha Ethanolamide Lipid Maps(R) MS Standard;N-(9S,11R,15S-trihydroxy-5Z,13E-prostadienoyl)-ethanolamine;Prostaglandin F2.alpha. Ethanolamide;LMFA03010075;11-epi PGF2alpha-EA;iPF2alpha-III Ethanolamide;SCHEMBL7602862;Prostaglandin F2?? Ethanolamide;CHEBI:53081;HMS3648N17;Prostaglandin F2 alpha Ethanolamide;AKOS040756277;8-iso Prostaglandin F2 alpha Ethanolamide;Prostaglandin F2alpha ethanolamide, >=98%;11 beta -Prostaglandin F2 alpha Ethanolamide;SR-01000946460;SR-01000946460-1;Q27123950;N-(2-hydroxyethyl)-9alpha,11alpha,15S-trihydroxy-(8beta)-prosta-5Z,13E-dien-1-amide;(5Z,9alpha,11alpha,13E,15S)-9,11,15-trihydroxy-N-(2-hydroxyethyl)prosta-5,13-dien-1-amide

Suppliers and Price of PGF2alpha-EA

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
Prostaglandin F2α ethanolamide ≥98%
5mg
$ 479.00

Cayman Chemical
Prostaglandin F2α Ethanolamide ≥98%
10mg
$ 456.00

Cayman Chemical
Prostaglandin F2α Ethanolamide ≥98%
5mg
$ 257.00

Cayman Chemical
Prostaglandin F2α Ethanolamide MaxSpec? Standard ≥95%
100μg
$ 93.00

Cayman Chemical
Prostaglandin F2α Ethanolamide ≥98%
1mg
$ 57.00

American Custom Chemicals Corporation
N-(2-HYDROXYETHYL)-9A,11A,15S-TRIHYDROXY-PROSTA-5Z,13E-DIEN-1-AMIDE 95.00%
5MG
$ 501.35

Total 6 raw suppliers

Chemical Property of PGF2alpha-EA

Chemical Property:

Flash Point:14 °C
PSA：110.02000
LogP:2.45770
Storage Temp.:−20°C
XLogP3:1.8
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:14
Exact Mass:397.28282334
Heavy Atom Count:28
Complexity:480

Purity/Quality:

95% ^*data from raw suppliers

Prostaglandin F2α ethanolamide ≥98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:F,Xi
Statements: 11-36/37/38
Safety Statements: 7-16-26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCC(C=CC1C(CC(C1CC=CCCCC(=O)NCCO)O)O)O
Isomeric SMILES:CCCCC[C@@H](/C=C/[C@H]1[C@@H](C[C@@H]([C@@H]1C/C=C\CCCC(=O)NCCO)O)O)O
Description Prostaglandin F2α ethanolamide (PGF2α-EA) is produced by COX-2 metabolism of the endogenous cannabinoid, arachidonoyl ethanolamide (AEA), found in brain, liver, and other mammalian tissues. AEA can be metabolized directly by the sequential action of COX-2 and specific PG synthases to produce ethanolamide congeners of the classical PGs. PGF2α-EA has also been reported to be biosynthesized by this mechanism when AEA was infused into the lung and liver of living mice. PGF2α-EA is a potent dilator (EC50 = 58 nM) of the cat iris sphincter, which is a model system for testing potential intraocular hypotensive agents.

Technology Process of PGF2alpha-EA

There total 1 articles about PGF2alpha-EA which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%