4-(4-Bromo-phenyl)-2-phenyl-5,7-dihydro-1,7-diaza-dibenzo[a,c]cyclohepten-6-one

Base Information

• Chemical Name: 4-(4-Bromo-phenyl)-2-phenyl-5,7-dihydro-1,7-diaza-dibenzo[a,c]cyclohepten-6-one
• CAS No.: 205048-72-2
• Molecular Formula: C₂₅H₁₇BrN₂O
• Molecular Weight: 441.327
• Mol file: 205048-72-2.mol

Synonyms:4-(4-Bromo-phenyl)-2-phenyl-5,7-dihydro-1,7-diaza-dibenzo[a,c]cyclohepten-6-one

Chemical Property of 4-(4-Bromo-phenyl)-2-phenyl-5,7-dihydro-1,7-diaza-dibenzo[a,c]cyclohepten-6-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(4-Bromo-phenyl)-2-phenyl-5,7-dihydro-1,7-diaza-dibenzo[a,c]cyclohepten-6-one

There total 3 articles about 4-(4-Bromo-phenyl)-2-phenyl-5,7-dihydro-1,7-diaza-dibenzo[a,c]cyclohepten-6-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1H-[1]benzazepin-2,5(3H,4H)-dione (16511-38-9) → 4-(4-Bromo-phenyl)-2-phenyl-5,7-dihydro-1,7-diaza-dibenzo[a,c]cyclohepten-6-one (205048-72-2)

Guidance literature:

Multi-step reaction with 2 steps

1: KOH / ethanol

2: ammonium ferric sulfate dodecahydrate, ammonium acetate, AcOH / 3 h / Heating

With ammonium acetate; potassium hydroxide; ammonium iron(III) sulfate dodecahydrate; acetic acid; In ethanol;

DOI:10.1021/jm970675l

Reference yield:

(2E)-3-(4-bromophenyl)-1-phenylprop-2-en-1-one (22966-09-2) → 4-(4-Bromo-phenyl)-2-phenyl-5,7-dihydro-1,7-diaza-dibenzo[a,c]cyclohepten-6-one (205048-72-2)

Guidance literature:

Multi-step reaction with 2 steps

1: KOH / ethanol

2: ammonium ferric sulfate dodecahydrate, ammonium acetate, AcOH / 3 h / Heating

With ammonium acetate; potassium hydroxide; ammonium iron(III) sulfate dodecahydrate; acetic acid; In ethanol;

DOI:10.1021/jm970675l

Reference yield:

4-[1-(4-Bromo-phenyl)-3-oxo-3-phenyl-propyl]-3,4-dihydro-1H-benzo[b]azepine-2,5-dione (1027245-31-3) → 4-(4-Bromo-phenyl)-2-phenyl-5,7-dihydro-1,7-diaza-dibenzo[a,c]cyclohepten-6-one (205048-72-2)

Guidance literature:

With ammonium acetate; ammonium iron(III) sulfate dodecahydrate; acetic acid; for 3h; Yield given; Heating;

DOI:10.1021/jm970675l

upstream raw materials:

4-[1-(4-Bromo-phenyl)-3-oxo-3-phenyl-propyl]-3,4-dihydro-1H-benzo[b]azepine-2,5-dione

1H-[1]benzazepin-2,5(3H,4H)-dione

(2E)-3-(4-bromophenyl)-1-phenylprop-2-en-1-one