methyl 3,4,6-tri-O-acetyl-2-deoxy-2-(4-nitrophenoxycarbonylamino)-β-D-glucopyranoside

Base Information

• Chemical Name: methyl 3,4,6-tri-O-acetyl-2-deoxy-2-(4-nitrophenoxycarbonylamino)-β-D-glucopyranoside
• CAS No.: 130539-23-0
• Molecular Formula: C₂₀H₂₄N₂O₁₂
• Molecular Weight: 484.417
• Mol file: 130539-23-0.mol

Synonyms:methyl 3,4,6-tri-O-acetyl-2-deoxy-2-(4-nitrophenoxycarbonylamino)-β-D-glucopyranoside

Chemical Property of methyl 3,4,6-tri-O-acetyl-2-deoxy-2-(4-nitrophenoxycarbonylamino)-β-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 3,4,6-tri-O-acetyl-2-deoxy-2-(4-nitrophenoxycarbonylamino)-β-D-glucopyranoside

There total 1 articles about methyl 3,4,6-tri-O-acetyl-2-deoxy-2-(4-nitrophenoxycarbonylamino)-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

bis-(p-nitrophenyl) carbonate (5070-13-3) + methyl O-3,4,6-tri-O-acetyl-2-amino-2-deoxy-β-D-glucopyranoside (42854-52-4) → methyl 3,4,6-tri-O-acetyl-2-deoxy-2-(4-nitrophenoxycarbonylamino)-β-D-glucopyranoside (130539-23-0)

Guidance literature:

With benzotriazol-1-ol; In dichloromethane; for 20h; Ambient temperature;

DOI:10.1016/0008-6215(90)80029-3

Reference yield: 92.0%

methyl 3,4,6-tri-O-acetyl-2-deoxy-2-(4-nitrophenoxycarbonylamino)-β-D-glucopyranoside (130539-23-0) + glycyl-L-phenylalanine benzyl ester hydrochloride → N-(methyl 3,4,6-tri-O-acetyl-2-amino-2-deoxy-β-D-glucopyranoside)-N'-carbonyl-glycyl-L-phenyl-alanine benzyl ester

Guidance literature:

With triethylamine; In pyridine; at 20 ℃; for 48h;

DOI:10.1016/S0008-6215(97)00236-X

Reference yield: 91.0%

methyl 3,4,6-tri-O-acetyl-2-deoxy-2-(4-nitrophenoxycarbonylamino)-β-D-glucopyranoside (130539-23-0) + benzylamine (100-46-9) → methyl 3,4,6-tri-O-acetyl-2-(3-benzylureido)-2-deoxy-β-D-glucopyranoside (130539-33-2)

Guidance literature:

In dichloromethane; Ambient temperature;

DOI:10.1016/0008-6215(90)80029-3

upstream raw materials:

bis-(p-nitrophenyl) carbonate

methyl O-3,4,6-tri-O-acetyl-2-amino-2-deoxy-β-D-glucopyranoside

Downstream raw materials:

N-(methyl 3,4,6-tri-O-acetyl-2-amino-2-deoxy-β-D-glucopyranoside)-N'-carbamoyl-glycine benzyl ester

methyl 3,4,6-tri-O-acetyl-2-(3-cyclohexylureido)-2-deoxy-β-D-glucopyranoside

methyl 3,4,6-tri-O-acetyl-2-deoxy-2-(3',3'-dicyclohexylureido)-β-D-glucopyranoside

methyl 3,4,6-tri-O-acetyl-2-(3-benzylureido)-2-deoxy-β-D-glucopyranoside