(R)-(+)-2-(Fluorodiphenylmethyl)pyrrolidine

Base Information

Chemical Name:(R)-(+)-2-(Fluorodiphenylmethyl)pyrrolidine
CAS No.:352535-00-3
Molecular Formula:C17H18 F N
Molecular Weight:255.335
Hs Code.:2933990090
European Community (EC) Number:631-537-4
DSSTox Substance ID:DTXSID60584250
Nikkaji Number:J2.711.418K
Wikidata:Q76511190
Mol file:352535-00-3.mol

Synonyms:352535-00-3;(R)-(+)-2-(Fluorodiphenylmethyl)pyrrolidine;(2R)-2-[Fluoro(diphenyl)methyl]pyrrolidine;(R)-(+)-2-(FLUORODIPHENYLMETHYL)PYRROLI&;SCHEMBL10326537;DTXSID60584250;AKOS015898108;(2R)-2-(FLUORODIPHENYLMETHYL)PYRROLIDINE;(R)-(+)-2-(Fluorodiphenylmethyl)pyrrolidine, optical purity ee: 98% (HPLC), 97%

Suppliers and Price of (R)-(+)-2-(Fluorodiphenylmethyl)pyrrolidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (R)-(+)-2-(Fluorodiphenylmethyl)pyrrolidine

Chemical Property:

Vapor Pressure:1.44E-05mmHg at 25°C
Refractive Index:n20/D 1.577(lit.)
Boiling Point:366.7°Cat760mmHg
Flash Point:175.6°C
PSA：12.03000
Density:1.098g/cm³
LogP:3.98050
XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:255.142327740
Heavy Atom Count:19
Complexity:261

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1CC(NC1)C(C2=CC=CC=C2)(C3=CC=CC=C3)F
Isomeric SMILES:C1C[C@@H](NC1)C(C2=CC=CC=C2)(C3=CC=CC=C3)F

Technology Process of (R)-(+)-2-(Fluorodiphenylmethyl)pyrrolidine

There total 1 articles about (R)-(+)-2-(Fluorodiphenylmethyl)pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 22348-32-9
(R)-α,α-diphenylprolinol

: 352535-00-3
(R)-2-(fluorodiphenylmethyl)pyrrolidine

Guidance literature:: With diethylamino-sulfur trifluoride; In dichloromethane; at 0 - 20 ℃; for 6.5h; Inert atmosphere;
DOI:10.1055/s-0029-1218636

Reference yield: 77.0%

: 352535-00-3
(R)-2-(fluorodiphenylmethyl)pyrrolidine

: 1160851-02-4
(R)-2-(fluorodiphenylmethyl)pyrrolidinium perchlorate

Guidance literature:: (R)-2-(fluorodiphenylmethyl)pyrrolidine; With perchloric acid; In diethyl ether; ethanol; at 20 ℃; for 0.0833333h; pH=4;

With pyrrolidine; In diethyl ether; ethanol; pH=8;