3-DIMETHYLAMINOBENZOIC ANHYDRIDE

Base Information

• Chemical Name: 3-DIMETHYLAMINOBENZOIC ANHYDRIDE
• CAS No.: 4629-50-9
• Molecular Formula: C18H20 N2 O3
• Molecular Weight: 312.36
• Mol file: 4629-50-9.mol

Synonyms:Benzoicacid, 3-(dimethylamino)-, anhydride (9CI); Benzoic acid, m-(dimethylamino)-,anhydride (7CI,8CI); 3-(Dimethylamino)benzoic anhydride

Chemical Property of 3-DIMETHYLAMINOBENZOIC ANHYDRIDE

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 110-114℃
• Refractive Index: 1.614
• Boiling Point: 483.167°C at 760 mmHg
• Flash Point: 246.011°C
• PSA: 49.85000
• Density: 1.189g/cm³
• LogP: 2.81580

Purity/Quality:

97% ^*data from raw suppliers

3-DIMETHYLAMINOBENZOIC ANHYDRIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-DIMETHYLAMINOBENZOIC ANHYDRIDE

There total 3 articles about 3-DIMETHYLAMINOBENZOIC ANHYDRIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(dimethylamino)benzoyl chloride (54263-82-0) → 3-(dimethylamino)benzoic anhydride (4629-50-9)

Guidance literature:

With 2-aminopyrimidine; triethylamine; In dichloromethane;

DOI:10.1071/ch99145

Reference yield:

3-(dimethylamino)benzoic acid (99-64-9) → 3-(dimethylamino)benzoic anhydride (4629-50-9)

Guidance literature:

Multi-step reaction with 2 steps

1: oxalyl chloride; pyridine / CH₂Cl₂

2: NEt₃; 2-aminopyrimidine / CH₂Cl₂

With pyridine; 2-aminopyrimidine; oxalyl dichloride; triethylamine; In dichloromethane;

DOI:10.1071/ch99145

Reference yield:

→ 3-(dimethylamino)benzoic anhydride (4629-50-9)

Guidance literature:

1-(3-Hydroxy-propyl)-1H-benzotriazol in CHCl3, 1. Triethylamin und 3-Dimethylamino-benzoesaeure-chlorid-hydrochlorid in CHCl3, 20grad, mehrere h, 2. Siedetemp., 1 h, als Nebenprod.;

upstream raw materials:

3-(dimethylamino)benzoyl chloride

3-(dimethylamino)benzoic acid

Downstream raw materials:

N-{3-[3-(3-Dimethylamino-phenyl)-3-oxo-propionyl]-4-hydroxy-phenyl}-acetamide

Refernces