(1R,5S)-AH 019

Base Information

Chemical Name:(1R,5S)-AH 019
CAS No.:330625-46-2
Molecular Formula:C₂₂H₂₇NO
Molecular Weight:321.462
Hs Code.:

Synonyms:(1R,5S)-AH 019

Suppliers and Price of (1R,5S)-AH 019

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (1R,5S)-AH 019

Chemical Property:

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Technology Process of (1R,5S)-AH 019

There total 6 articles about (1R,5S)-AH 019 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: Acetic acid 3-((1R,5S)-2-phenethyl-2-aza-bicyclo[3.3.1]non-5-yl)-phenyl ester

: 330625-46-2
(1R,5S)-AH 019

Guidance literature:: With sodium hydroxide; In methanol; at 0 ℃;
DOI:10.1016/S0968-0896(02)00219-5

Reference yield:

: 103-63-9
1-phenyl-2-bromoethane

: 168135-17-9
(1R,5S)-3-(2-Aza-bicyclo[3.3.1]non-5-yl)-phenol

: 330625-46-2
(1R,5S)-AH 019

Guidance literature:: With sodium hydrogencarbonate; In N,N-dimethyl-formamide; at 80 ℃; for 2h;
DOI:10.1016/S0968-0896(02)00219-5

Reference yield:

: 28623-84-9
(-)-(1R,5S)-5-(3-hydroxyphenyl)-2-methyl-2-azabicyclo<3.3.1>nonane

: 330625-46-2
(1R,5S)-AH 019

Guidance literature:: Multi-step reaction with 5 steps

1: 1 h / 90 °C

2: sodium bicarbonate / toluene / 15 h / Heating

3: zinc; AcOH / H₂O / 3 h / 20 °C

4: sodium bicarbonate / dimethylformamide / 2 h / 80 °C

5: 750 mg / NaOH / methanol / 0 °C

With sodium hydroxide; sodium hydrogencarbonate; acetic acid; zinc; In methanol; water; N,N-dimethyl-formamide; toluene;
DOI:10.1016/S0968-0896(02)00219-5