bis[4-(3′,5′-di-tert-butylphenyl)-7-methoxy-2-methylindenyl]dimethylsilane

Base Information

• Chemical Name: bis[4-(3′,5′-di-tert-butylphenyl)-7-methoxy-2-methylindenyl]dimethylsilane
• CAS No.: 1379658-33-9
• Molecular Formula: C₅₂H₆₈O₂Si
• Molecular Weight: 753.196
• Mol file: 1379658-33-9.mol

Synonyms:bis[4-(3′,5′-di-tert-butylphenyl)-7-methoxy-2-methylindenyl]dimethylsilane

Chemical Property of bis[4-(3′,5′-di-tert-butylphenyl)-7-methoxy-2-methylindenyl]dimethylsilane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of bis[4-(3′,5′-di-tert-butylphenyl)-7-methoxy-2-methylindenyl]dimethylsilane

There total 8 articles about bis[4-(3′,5′-di-tert-butylphenyl)-7-methoxy-2-methylindenyl]dimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

2-methyl-4-methoxy-7-(3,5-di-tert-butylphenyl)-1H-indene (1379658-32-8) + dimethylsilicon dichloride (75-78-5,30107-43-8) → bis[4-(3′,5′-di-tert-butylphenyl)-7-methoxy-2-methylindenyl]dimethylsilane (1379658-33-9)

Guidance literature:

With n-butyllithium; In 1,4-dioxane; hexane; toluene; at -20 - 60 ℃;

DOI:10.1002/chem.201103547

Reference yield:

4-(3',5'-di-tert-butylphenyl)-7-methoxy-2-methylindene (1393604-93-7) + dimethylsilicon dichloride (75-78-5,30107-43-8) → bis[4-(3′,5′-di-tert-butylphenyl)-7-methoxy-2-methylindenyl]dimethylsilane (1379658-33-9)

Guidance literature:

4-(3',5'-di-tert-butylphenyl)-7-methoxy-2-methylindene; With n-butyllithium; copper(l) cyanide; In tetrahydrofuran; hexane; toluene; at -20 ℃; for 4h;

dimethylsilicon dichloride; In tetrahydrofuran; hexane; toluene; at 20 ℃; for 24h;

Reference yield:

1-bromo-3,5-di-tert-butylbenzene (22385-77-9) → bis[4-(3′,5′-di-tert-butylphenyl)-7-methoxy-2-methylindenyl]dimethylsilane (1379658-33-9)

Guidance literature:

Multi-step reaction with 3 steps

1: magnesium / tetrahydrofuran; diethyl ether / -60 - 20 °C / Reflux

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / ethanol; toluene / 72 h / Reflux

3: n-butyllithium / 1,4-dioxane; hexane; toluene / -20 - 60 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; n-butyllithium; sodium carbonate; magnesium; In tetrahydrofuran; 1,4-dioxane; diethyl ether; ethanol; hexane; toluene;

DOI:10.1002/chem.201103547

upstream raw materials:

4-bromo-7-methoxy-2-methyl-2,3-dihydro-1H-inden-1-one

2-methyl-4-methoxy-7-(3,5-di-tert-butylphenyl)-1H-indene

dimethylsilicon dichloride

7-bromo-4-methoxy-2-methyl-1H-indene