2-[(pyridin-2-yl)methylamino]-4-tert-butyl-6-(triphenylmethyl)phenol

Base Information

• Chemical Name: 2-[(pyridin-2-yl)methylamino]-4-tert-butyl-6-(triphenylmethyl)phenol
• CAS No.: 1496521-72-2
• Molecular Formula: C₃₅H₃₄N₂O
• Molecular Weight: 498.668
• Mol file: 1496521-72-2.mol

Synonyms:2-[(pyridin-2-yl)methylamino]-4-tert-butyl-6-(triphenylmethyl)phenol

Chemical Property of 2-[(pyridin-2-yl)methylamino]-4-tert-butyl-6-(triphenylmethyl)phenol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-[(pyridin-2-yl)methylamino]-4-tert-butyl-6-(triphenylmethyl)phenol

There total 3 articles about 2-[(pyridin-2-yl)methylamino]-4-tert-butyl-6-(triphenylmethyl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.8%

2-[(pyridin-2-yl)methyleneamino]-4-tert-butyl-6-(triphenylmethyl)phenol (1496521-66-4) → 2-[(pyridin-2-yl)methylamino]-4-tert-butyl-6-(triphenylmethyl)phenol (1496521-72-2)

Guidance literature:

With sodium tetrahydroborate; In ethanol; at 20 ℃; for 5h; Inert atmosphere; Schlenk technique;

DOI:10.1021/om4009636

Reference yield:

4-(tert-butyl)-6-(triphenylmethyl)phenol (97358-11-7) → 2-[(pyridin-2-yl)methylamino]-4-tert-butyl-6-(triphenylmethyl)phenol (1496521-72-2)

Guidance literature:

Multi-step reaction with 4 steps

1: acetic acid; nitric acid

2: acetic acid; zinc; ammonium chloride / ethanol; water / Reflux

3: acetic acid / ethanol / 6 h / Inert atmosphere; Schlenk technique; Reflux

4: sodium tetrahydroborate / ethanol / 5 h / 20 °C / Inert atmosphere; Schlenk technique

With sodium tetrahydroborate; nitric acid; ammonium chloride; acetic acid; zinc; In ethanol; water;

DOI:10.1021/om4009636

Reference yield:

C29H27NO3 → 2-[(pyridin-2-yl)methylamino]-4-tert-butyl-6-(triphenylmethyl)phenol (1496521-72-2)

Guidance literature:

Multi-step reaction with 3 steps

1: acetic acid; zinc; ammonium chloride / ethanol; water / Reflux

2: acetic acid / ethanol / 6 h / Inert atmosphere; Schlenk technique; Reflux

3: sodium tetrahydroborate / ethanol / 5 h / 20 °C / Inert atmosphere; Schlenk technique

With sodium tetrahydroborate; ammonium chloride; acetic acid; zinc; In ethanol; water;

DOI:10.1021/om4009636

upstream raw materials:

2-[(pyridin-2-yl)methyleneamino]-4-tert-butyl-6-(triphenylmethyl)phenol

4-(tert-butyl)-6-(triphenylmethyl)phenol