Technology Process of benzyl ether of 3,7,15,19,23-pentamethyl-11-formyltetraeicosa-2Z,6Z,10E,14Z,18Z,22-hexaen-1-ol
There total 10 articles about benzyl ether of 3,7,15,19,23-pentamethyl-11-formyltetraeicosa-2Z,6Z,10E,14Z,18Z,22-hexaen-1-ol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 1) LDA / 1) THF, hexane, -5 deg C, 40 min, 2a) -70 deg C, 10 min, b) 4 h, -40 deg C
3: 90 percent / NaBH4 / ethanol / 1.5 h / 20 °C
4: 1) pyridine sulfotrioxide, 2) LiAlH4 / 1) THF, 2 h, 0 deg C, 2a) -30 deg C, b) 20 deg C, 4 days
5: 72 percent / H2SO4 / H2O; acetone / 4 h / Heating
With
sodium tetrahydroborate; lithium aluminium tetrahydride; sulfuric acid; sulfur trioxide pyridine complex; lithium diisopropyl amide;
In
ethanol; water; acetone;
DOI:10.1007/BF00963008
- Guidance literature:
-
Multi-step reaction with 5 steps
2: 90 percent / NaBH4 / ethanol / 1.5 h / 20 °C
3: 1) pyridine sulfotrioxide, 2) LiAlH4 / 1) THF, 2 h, 0 deg C, 2a) -30 deg C, b) 20 deg C, 4 days
4: 72 percent / H2SO4 / H2O; acetone / 4 h / Heating
With
sodium tetrahydroborate; lithium aluminium tetrahydride; sulfuric acid; sulfur trioxide pyridine complex;
In
ethanol; water; acetone;
DOI:10.1007/BF00963008
- Guidance literature:
-
Multi-step reaction with 5 steps
2: 90 percent / NaBH4 / ethanol / 1.5 h / 20 °C
3: 1) pyridine sulfotrioxide, 2) LiAlH4 / 1) THF, 2 h, 0 deg C, 2a) -30 deg C, b) 20 deg C, 4 days
4: 72 percent / H2SO4 / H2O; acetone / 4 h / Heating
With
sodium tetrahydroborate; lithium aluminium tetrahydride; sulfuric acid; sulfur trioxide pyridine complex;
In
ethanol; water; acetone;
DOI:10.1007/BF00963008
