3-Cbz-4-phenyl-[1,2,3]oxathiazinane 2,2-dioxide

Base Information

• Chemical Name: 3-Cbz-4-phenyl-[1,2,3]oxathiazinane 2,2-dioxide
• CAS No.: 1202160-37-9
• Molecular Formula: C₁₇H₁₇NO₅S
• Molecular Weight: 347.392
• Mol file: 1202160-37-9.mol

Synonyms:3-Cbz-4-phenyl-[1,2,3]oxathiazinane 2,2-dioxide

Chemical Property of 3-Cbz-4-phenyl-[1,2,3]oxathiazinane 2,2-dioxide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Cbz-4-phenyl-[1,2,3]oxathiazinane 2,2-dioxide

There total 1 articles about 3-Cbz-4-phenyl-[1,2,3]oxathiazinane 2,2-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

(S)-4-phenyl-[1,2,3]oxathiazinane 2,2-dioxide + benzyl chloroformate (501-53-1,94274-21-2) → 3-Cbz-4-phenyl-[1,2,3]oxathiazinane 2,2-dioxide (1202160-37-9)

Guidance literature:

(S)-4-phenyl-[1,2,3]oxathiazinane 2,2-dioxide; With sodium t-butanolate; In 1,2-dimethoxyethane; at 20 ℃; Inert atmosphere;

benzyl chloroformate; In 1,2-dimethoxyethane; for 10h; Inert atmosphere;

DOI:10.1021/jo902176s

Reference yield: 83.0%

3-Cbz-4-phenyl-[1,2,3]oxathiazinane 2,2-dioxide (1202160-37-9) → (-)-(3S)-3-((benzyloxycarbonyl)amino)-3-phenylpropanol (869468-32-6,888298-05-3)

Guidance literature:

3-Cbz-4-phenyl-[1,2,3]oxathiazinane 2,2-dioxide; With water; In acetonitrile; at 75 ℃; for 24h; Inert atmosphere;

With hydrogenchloride; In water; ethyl acetate; acetonitrile; at 20 ℃; for 1h; Inert atmosphere;

With sodium hydroxide; In water; ethyl acetate; acetonitrile; Inert atmosphere;

DOI:10.1021/jo902176s

upstream raw materials:

benzyl chloroformate

Downstream raw materials:

(-)-(3S)-3-((benzyloxycarbonyl)amino)-3-phenylpropanol