γ-(α-tert-butyloxy-Z-glutamyl)choline bromide

Base Information

• Chemical Name: γ-(α-tert-butyloxy-Z-glutamyl)choline bromide
• CAS No.: 103897-82-1
• Molecular Formula: Br*C₂₂H₃₅N₂O₆
• Molecular Weight: 503.434
• Mol file: 103897-82-1.mol

Synonyms:γ-(α-tert-butyloxy-Z-glutamyl)choline bromide

Chemical Property of γ-(α-tert-butyloxy-Z-glutamyl)choline bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of γ-(α-tert-butyloxy-Z-glutamyl)choline bromide

There total 2 articles about γ-(α-tert-butyloxy-Z-glutamyl)choline bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

methyl bromide (74-83-9) + α-tert-butyl γ-(N,N-dimethylamino)ethyl Z-glutamate (101463-49-4) → γ-(α-tert-butyloxy-Z-glutamyl)choline bromide (103897-82-1)

Guidance literature:

In ethyl acetate; benzene; Ambient temperature;

DOI:10.1248/cpb.33.5062

Reference yield:

N-(benzyloxycarbonyl)-L-glutamic acid α-t-butyl ester dicyclohexylamine salt (34897-61-5) → γ-(α-tert-butyloxy-Z-glutamyl)choline bromide (103897-82-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 98 percent / benzene; ethyl acetate / 16 h / 90 °C

2: 96 percent / benzene; ethyl acetate / Ambient temperature

In ethyl acetate; benzene;

DOI:10.1248/cpb.33.5062

Reference yield: 91.0%

γ-(α-tert-butyloxy-Z-glutamyl)choline bromide (103897-82-1) → γ-(Z-glutamyl)choline bromide (101463-46-1)

Guidance literature:

With trifluoroacetic acid; In dichloromethane;

DOI:10.1248/cpb.33.5062

upstream raw materials:

methyl bromide

α-tert-butyl γ-(N,N-dimethylamino)ethyl Z-glutamate

N-(benzyloxycarbonyl)-L-glutamic acid α-t-butyl ester dicyclohexylamine salt

Downstream raw materials:

γ-(Z-glutamyl)choline bromide